无线激光打靶系统设计

为了提高适应性和实用性,设计了一种新型的无线靶枪分离型激光打靶器。该打靶器采用无线发送技术,把信息通过无线发送模块发送出去,接收系统再通过无线接收模块把信息取出,再用汉字显示屏和实时显示系统显示打靶信息,并可用计算机实时显示打靶者的成绩,具有精度高、能自动判断、显示环数、方位等特点。介绍了该打靶系统的基本工作原理,并对硬件和软件的设计作了详细分析。     

免疫脂质体的研究进展

就免疫脂质体的组成、结构、制备方法、临床应用进行讨论,为脂质体的开发与临床应用提供有用的情报。同时提供了一些提高免疫脂质体特定靶向性的一些方法。     

无线激光打靶系统设计

为了提高适应性和实用性,设计了一种新型的无线靶枪分离型激光打靶器。该打靶器采用无线发送技术,把信息通过无线发送模块发送出去,接收系统再通过无线接收模块把信息取出,再用汉字显示屏和实时显示系统显示打靶信息,并可用计算机实时显示打靶者的成绩,具有精度高、能自动判断、显示环数、方位等特点。介绍了该打靶系统的基本工作原理,并对硬件和软件的设计作了详细分析。     

Perforin and its role in T lymphocyte-mediated cytolysis

The killing mediated by cytotoxic T lymphocytes (CTL) represents an important mechanism in the immune defence against tumors and virus infections. The lytic mechanism has been proposed to consist of a polarized secretion of granule-stored molecules, occurring on effector-target cell contact. By electron microscopy, membrane deposited, pore-like lesions are detected on the target cell membrane during cytolysis by CTL. These structures resembled strikingly pores formed during complement attack.Granules of CTL isolated by nitrogen cavitation and Percoll gradient centrifugation were shown to retain cytotoxic activity. Further purification of proteins stored in these granules led to the discovery of a membranolytic protein named perforin which was capable of polymerizing into pore-like structures. In addition to this cytolytic protein, a set of serine esterases was found as well as lysosomal enzymes and proteoglycans, whose function are not yet clearly defined. The role of perforin in the cytotoxic process is currently being explored by ablating the active gene in mice.     

转基因鱼的研究及其发展前景

20年来国内外主要进行了快速生长转基因鱼、抗寒(耐寒)转基因鱼、抗病转基因鱼和其他抗性转基因鱼的研究,常用的鱼类基因转移技术有显微注射法、精子载体法、电穿孔法、基因枪法、胚胎干细胞载体、脂质体法和缺陷性病毒感染法等基因转移方法。转基因鱼的安全性和遗传稳定性有望通过进一步的科研攻关得到解决,转基因鱼的生产应用前景广阔。