IMPLICITIZATION OF PARTIAL DIFFERENTIAL RATIONAL PARAMETRIC EQUATIONS

In this paper, we propose algorithms for the following problems in the implicitization of a set of partial differential rational parametric equations P. （1）To find a characteristic set for the implicit prime ideal of P; （2） To find a canonical representation for the image of P; （3）To decide whether the parameters of P are independent, and if not, to re-parameterize P so that the new parametric equations have independent parameters; （4） To compute the inversion maps of P, and as a consequence, to decide whether P is proper.     

音乐欣赏本体性质探究

音乐欣赏的本体性质是音乐美学领域中重要很难回答的问题。音乐欣赏通过听觉来审美，在创造过程中，完成感性与理性的相互结合与统一。从音乐材料，结构环节和功能作用三方面断定，材料是物质和精神的统一性，结合是约定的感性材料与理性材料的结合、音乐欣赏有其独特的功能和广泛的联系，是一门介于社会科学与自然科学之间的交叉学科。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

关于振动模态参数识别的注记

回顾了关于整体拟合的分母多项式系数的争议,论证了Richardson文献中所提供的参数精度不高的原因并非源于Richardson的错误.指出一个经典考核算例的仿真传递函数生成公式不同于复模态理论提供的公式,讨论了两者之间的关系.表1,参9.     

高校图书馆的阅读治疗服务对大学生心理健康的作用

分析了大学生产生心理疾病的原因,探讨了"阅读治疗"对大学生心理健康的作用,提出了高校图书馆开展阅读治疗的措施。     

微波与生物组织的相互作用及微波理疗中若干实际考虑

本文论述了描述微波与生物组织相互作用的数学表达式,讨论工作频率选择、透入深度、反射、极化、泄漏及防护等实际问题。     

高校招生改革的理性思考

高校招生改革是高校各项工作的首要内容，要把高校招生作为扩大内需，刺激经济增长的重要举措。扩招与择校是对传统招生制度的重要改革，但也存在一些政策、措施方面的问题。这就要求招生部门、教育部门和政策专家必须找到一个结合点，这个结合点就是不可违逆的传统和现代性的和谐结合，或曰国家计划和市场经济的和谐结合。     

C─余模和有理C~＊─模

众所周知，余模和有理模在Ｈｏｐｆ代数理论的研究中发挥着重要的作用。本文将给出余模与有理模之间的关系，论证在特殊条件下Ｍ＊的最大有理Ｃ＊─子模的刻划问题。     

|x|在扩展的Chebyshev结点的有理插值

研究|x|在扩展的Chebyshev结点的有理插值,得到逼近阶为O(1/(nln n)).通过数值计算发现相同逼近阶的误差与结点的密集度、结点所在曲线的凹凸性有关.     

Research advances in gene therapy for Parkinson's disease

During the long period of time when people have been seeking for an effective therapeutic method for PD, the gene therapy has shown greater and greater advantages over other methods. It can be performed mainly in two ways: ex vivo and in vivo. With the former, TH gene as well as some neurotrophic factor genes (such as GDNF, BNDF genes) can be invited to some cell lines or primary cells thus forming engineered cells and then implanting them into brain. While with the latter, viral vectors including HSV-1, Ad, AAV that can be utilized to construct recombinant viruses, or non-virus vectors can be used to delived DNA into brain directly. The present review summarizes the recent research advances in the gene therapy for PD, and it is reasonable for us to predict a notable progress in prevention and treatment for PD in the next decade.