天津医科大学图书馆中文专业图书资源利用效率统计分析

以天津医科大学图书馆UNICORN集成管理系统的各项记录为数据源,挖掘整合了2004—2013年中文专业图书有关数据,从综合性、动态性角度,统计分析了图书购置数量、图书借阅数量及购书经费分布等有关数据,旨在为提高图书馆管理水平提供参考依据。     

带有非相参积累的序列统计恒虚警检测器

雷达检测中,为了改善检测性能经常采用非相参积累的方法以获取高信杂比的目标回波,本文讨论了平方律检波后带有非相参积累的序列统计恒虚警检测器,分析了Swerling起伏目标情况下的检测性能,并介绍了该检测器在实际工作中的一种应用。     

我院近7年剖宫产率及剖宫产指征变化的临床分析

目的：总结我院近7年剖宫产率及剖宫产指征的变化。方法：回顾性分析我院近7年来剖宫产孕妇的临床资料。结果：剖宫产率逐年升高,2000年为29%,2006年为54.30%,增加1.87倍;2000年-2003年剖宫产的指征难产排第一位,而近3年,社会因素占第一位。结论：剖宫产率升高主要与社会因素有关,降低剖宫产率的关键是严格掌握剖宫产指征,尽量减少因社会因素而行剖宫产术。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

“926”植物生长调节剂的药效作用及机理研究

试验表明，“９２６”植物生长调节剂对植物种子活力、根系活力、植物生长发育具有明显的促进作用。用“９２６”浸稻种和玉米种，可提高发芽势、发芽率，增加次生根数和次生根长。苗期施药，同样可促进幼苗生长发育、促进根系发育、增加分蘖、分枝，提高成穗率。其它生育期施药，可分别提高成稳率、穗粒数、粒重，显著提高作物产量。     

汽车拖拉机转向机构的优化设计

本文提出用一种新的时间离散化方法对汽车拖拉机的转向机构进行优化设计．该离散化方法是按被实现函数变化率的大小划分时间单元，在被实现函数变化率较大的区域，分点较密；在率化率较小的区域，分点较稀．笔者还分别用等间距的时间离散化及切比雪夫时间离散化方法，对同一机构使用同一种优化方法进行了优化设计，并将三种计算结果进行了比较．结果表明，笔者提出的方法，没有增加计算工作量，而能提高计算精度．     

铸件成品率微机管理系统

建立了铸件成品率的数学模型，以实现铸件成品率的微机管理．该系统具有统计、分析、判断、优化等各项功能，满足了生产现场对铸件成本的控制．     

上皮生长因子预防心脏术后心包粘连的实验及临床研究

目的探讨上皮生长因子(EGF)对心脏术后心包粘连的预防作用.方法术中对犬心包内喷洒上皮生长因子3个月后,观察心包粘连情况;选先天性心脏病、房缺及室缺病人40例,术中心包内喷洒上皮生长因子,术后6个月、12个月经CT检查,判定心包粘连、增厚结果.结果在动物实验和临床研究中,实验组粘连程度显著低于对照组(P<0.01).结论 EGF心包内应用有明显预防心脏术后心包粘连的作用.     

籽瓜植株(地上部)的生长发育规律

对内蒙古地区有代表性的四个籽瓜品种植株(地上部)的生长发育进行了研究．结果表明：内蒙古籽瓜的全生育期为92-101d，籽瓜植株的生长发育可分为发芽期、幼苗期、伸蔓期和结果期，结果期分为前期(开花座果期)、中期(果实膨大期)、后期(种子成熟期)．发芽期、幼苗期以叶为生长中心，伸蔓期、结果前期以茎为生长中心，进入结果中期以果实为生长中心不同生育分期长短的差异主要表现在结果中期的差异上．     

非线性生育率阶段结构的收获模型

建立并分析了一类非线性生育率阶段结构的单种群的收获模型，得到了正平衡点全局稳定的条件，给出了最优收获策略．