带有临界增长的Kirchhoff方程极小能量变号解的存在性

为了深入研究Kirchhoff方程的性质,讨论了带有Hartree项和临界增长非线性项的Kirchhoff方程极小能量变号解的存在性。利用能量泛函在变号Nehari流形上的下确界C_λ收敛于0,得到空间E紧嵌入L~6(R~3)这一技术性结果。结果表明,利用限制变分方法和定量形变引理获得极小化序列对应的极小值点是该问题的非平凡解。研究方法在理论证明方面得到了良好的结果,对研究其他Kirchhoff方程解的存在性有一定的指导意义。     

黎锦明小说的艺术特色

在中国现代文学史上，黎锦明创作颇丰，曾是一位较为活跃的有影响的著名作家，有些作品在当时曾引起文坛的瞩目和社会的反响。长期以来，他和他的作品被人漠视和遗忘。实际上，他的小说在题材内容选取上很是广阔，在体式技法运用的多样性上更是有其独特之处。     

洱海区域新石器时代文化概述

根据现有考古资料,从考古学的角度,概述了洱海区域新石器时代文化遗址的分布与类型、文化特征及文化渊源,证实了该区域新石器文化是在古人类文化的基础上而产生,并不断地汲取其它文化因素,形成了自成一体的区域地方性新石器文化.     

靖西县新圩铝土矿地质特征及控矿因素

根据多年的实际工柞经验，论述了靖西新圩铝土矿床的地质特征及控矿因素。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

贵州凯里绿都小区的民族特色与生态环境

在民族地区开发、建设新小区,除了要考虑小区的现代生活环境、建筑功能、保温节能外,还应综合考虑小区的民族特色、绿色环保因素。以贵州凯里绿都小区建设为例,对民族地区小区规划、设计进行了探讨。     

反思对话式教学

教学本质上是沟通和合作的活动。对话式教学就是教育教学活动本身。它具有开放性和启发性、互动性和共享性的特征;要求对话主体理解和反思。当今对话式教学暴露出不少问题:教师操纵对话过程;对话停留在表面,难以深入下去;教师对待教学文本的态度不良;教学对话的物理环境条件差。解决这些问题,应采取一定的策略措施。     

对面向对象分析法进行比较评估的一种新方法

提出一种新的比较框架，其中包含了一系列面向对象分析（OOA）方法共同的基本特性．以5种著名的面向对象分析方法为例，阐述了如何通过它们的特性细节，对面向对象分析方法进行分析、比较和评估．     

“926”植物生长调节剂的药效作用及机理研究

试验表明，“９２６”植物生长调节剂对植物种子活力、根系活力、植物生长发育具有明显的促进作用。用“９２６”浸稻种和玉米种，可提高发芽势、发芽率，增加次生根数和次生根长。苗期施药，同样可促进幼苗生长发育、促进根系发育、增加分蘖、分枝，提高成穗率。其它生育期施药，可分别提高成稳率、穗粒数、粒重，显著提高作物产量。