卢卡奇物化观述评

卢卡奇认为物化导致了主体与客体、自由与必然的二元对立。异化不仅存在于经济领域中,还深入到人的意识中,物化的解决有赖于阶级意识。卢卡奇的物化观注重彰显人的主体性,在当时的情况下是可贵的。但他的缺陷也是不容忽视的:他未区分异化、对象化和物化概念,他对于物化的完全否定态度是片面的,同时他把异化的解决途径完全归于无产阶级的自我意识也是有待商榷的。     

Anaerobic microbial conversion of three hydroxycinnamic acids

Summary Caffeic, ferulic and synapic acid are anaerobically degraded by a microbial consortium via the reduction of the double bond of the side chain, the replacement of the nuclear hydroxyl group in position 4 by hydrogen, the demolition of the side chain by the loss of a C₁ unit.     

The lymphatic route. 1) Albumin and hyaluronidase modify the normal distribution of interferon in lymph and plasma

Summary When human recombinant interferon-₂ diluted in saline was injected s.c. into rabbits, the total amount recovered in thoracic lymph was less than 0.4%. Recoveries increased from 2- to 8-fold if interferon was injected in 4% albumin or with hyaluronidase, respectively. Albumin added to interferon acts as an interstitial fluid expander, thus favoring interferon absorption through lymphatics rather than blood capillaries. This strategy may increase the therapeutic index of interferon.This work was supported by Ministero Pubblica Istruzione and Progetto Finalizzato Oncologia, contract No. 84.00461.44, CNR, Roma.     

运动与性腺激素

身体运动对依赖于运动强度，运动持续时间和身体素质而变化的生殖激素具有一定的作用范围。一般来说，持续时间相对短的大强度运动可使血清睾酮水平提高，并改变其它激素的水平，但包括血液浓缩程度和体内激素廓清的降低抑或合成的加强等均使问题复杂变化。内分泌激素在机体对运动的反应和适应方面起到举足轻重的作用，同时影响着运动后恢复阶段。     

植物组织培养中的pH值

在植物组织培养中 ,对于影响细胞分裂分化的 p H因子 ,人们对其真正的影响未引起足够的重视 .结合文献并通过实验发现 :环境 p H值对胞质 p H值、质膜透性、植物激素作用、生理代谢及培养物的生长和分化都存在不同程度影响 ,是植物组织培养中应加以重视的影响因子 .     

Isolation and characterization of a <Emphasis Type="Italic">Sinorhizobium fredii</Emphasis> mutant that cannot utilize proline as the sole carbon and nitrogen source

Sinorhizobium fredii strain HN01 can use proline as the sole carbon and nitrogen source. A mutant strain GXHN100 unable to catabolize proline was screened from 6000 Tn5gusA5 random insertional mutants of S.fredii strain HN01. Sequencing analysis showed that an open reading frame, named pmrA (proline metabolic relative), was inserted by the Tn5gusA5. A positive clone, namedp GXHN100 which containing 3.3kb foreign DNA fragment of S.fredii strain HN01, was isolated from a partial gene library of S.fredii HN01 by colony in situ hybridization. Sequence analysis showed that pGXHN100 contained the entire pmrA gene. The 3.3kb DNA fragment of pGXHN100 was cloned into a broad-host-range cosmid vector pLAFR3 to form plasmid pGXHN200 which was subsequently introduced into GXHN100 to form a complemented strain GXHN200. Plant test showed that GXHN100 was effective and no obvious changes in nitrogenase activity comparing with parental strain. But GXHN100 nodulated 2 days later on soybean and its nodulation efficiency and competitiveness were decreased.The complemented strain GXHN200 restored the nodulation efficiency and competitiveness of GXHN100 to the wild type.     

猪脂肪组织离体代谢调节的研究概况

综述了猪体脂肪组织离体合成代谢和分解代谢的研究概况以及其它物种离体脂肪组织代谢调节的一些研究进展．特别注重胰岛素、肾上腺素等激素对脂肪组织合成及分解代谢的调节作用．     

Accumulation of purine catabolites in solid tumors exposed to therapeutic hyperthermia

Intensified adenosine triphosphate (ATP) degradation following therapeutic hyperthermia is often observed in solid tumors. As a result, accumulation of purine catabolites can be expected together with formation of protons at several stages during degradation to the final product, uric acid. Proton formation in turn can contribute to the development of heat-induced acidosis. Furthermore, oxidation of hypoxanthine and xanthine may result in generation of reactive oxygen species, which may lead to DNA damage, lipid peroxidation and protein denaturation, thus also contributing to heat-induced cytotoxicity. In hyperthermia experiments a tumor-size-dependent, significant increase in the levels of the following catabolites has been demonstrated: [IMP+GMP] (sum of guanosine and inosine monophosphate levels), inosine, hypoxanthine, xanthine and uric acid, along with a drop in ATP and guanosine triphosphate (GTP) levels. These data suggest that formation of reactive oxygen species and protons during purine degradation may indeed play a significant role in the antitumor effect of hyperthermia.