Synthesis and antimutagenic effects of selena-morpholine hydrate

The synthesis of selenamorpholine hydrate was described and its antimutagenic effects were investigated by the Ames tests. The results indicated that the mutation induced by the indirect mutagen 2-AF was inhibited obviously by selenamorpholine hydrate at the dosage of Se 0. 16～100 μg /dish for 35.8%～53.7%(TA97) and the mutation induced by direct mutagen Dexon was inhibited for 6.2%～30.0%(TA97) and 2.3%～34.1%(TA100). The mutagenesis of the indirect mutagen cyclophosphamide was suppressed for 5.4%～16.1% by selenamorpholine hydrate at the dosage of Se 0. 16～100 μg /dish.     

花青素生物学作用研究进展

花青素是一类广泛存在于植物的花、果、茎、叶和种子中的水溶性天然色素,具有很高生物活性的黄酮多酚类化合物,对人体无毒副作用。近年来,众多学者对花青素做了较为详细深入的研究。回顾了目前花青素的研究成果,力求为进一步研究开发花青素生物活性提供资料。