复合式小梁切除术的临床观察

目的 :观察复合式小梁切除术的手术成功率及术后并发症。方法 :对23例(27眼)小梁切除术中应用0 4mg/ml的丝裂霉素C ,联合前房穿刺 ,外置巩膜瓣可拆除缝合的方法进行观察。结果 :23例中功能滤过泡达100%,术后6mo眼压稳定 ,术后仅1例发生Ⅱ级浅前房。结论 :复合式小梁切除术不仅提高了抗青光眼手术的效果 ,而且大大减少了并发症的发生     

电视胸腔镜下微创脊柱侧弯前路松解术的初期临床结果

探讨电视胸腔镜在严重脊柱侧弯前路松解中的应用价值,并对其初期临床结果进行分析.2001年11月-2002年8月,共11例严重脊柱侧弯患者接受电视胸腔镜下前路松解,均为女性,特发性胸椎脊柱侧弯,年龄14～17岁.冠状面Cobb角90°～100°,Risser征+++～++++,松解范围T5～T12,松解节段5～7.术后行牵引二周再行后路TSRH矫形内固定术.术中出血量为100～150mL,手术时间180～220min,术后引流量520～650mL,引流时间48～96h,二期后路手术矫正率平均为58%.电视胸腔镜下脊柱侧弯的前路松解在不影响矫形手术效果的同时,能减少组织损伤,降低感染可能,减轻术后疼痛,缩短病人的康复时间.     

前交叉韧带运动损伤临床治疗的进展

前交叉韧带是膝关节最重要的稳定因素,对膝关节起着导向和限制作用.前交叉韧带断裂可以导致严重的关节不稳,从而严重影响运动功能;如未得到及时治疗,还会继发半月板、关节软骨损害和骨性关节炎等.近年来临床研究中发现,前交叉韧带断裂导致膝关节功能丧失,常常在一段时间内呈进行性加重的态势.因此,在治疗上需要从韧带的解剖、组织学和生物力学等各方面进行研究,完善前交叉韧带运动损伤的临床治疗.     

垂直旋转圆盘边缘液体滑移率及液柱形态

旋转圆盘表面液体与壁面之间存在切向相对滑移,液体的转速并不等于圆盘转速.利用高速摄影拍摄圆盘边缘液体形态,用软件Image J测量了液体的滑移率及液体头液滴与液柱的直径比.分析发现,垂直旋转圆盘不同区域的液体滑移率不同,随转速增加,各区域滑移率趋向相同,为10％～13％.圆盘表面的波动、边缘液体的形态会影响液体滑移率的...     

贝壳韧带微结构的高分辨扫描电镜研究

采用高分辨SEM及XRD对合浦珠母贝韧带进行了研究,结果表明,合浦珠母贝韧带无机相主要由文石组成.韧带具有明显的层状结构,同一生长层及相隔生长层中文石纤维呈一致定向排列,而相邻生长层文石纤维的定向明显不同,呈“交叉棱柱层”结构样式.合浦珠母贝韧带中文石纤维的直径为80~90 nm,具有典型的2D光子晶体结构特征.     

Regulation of BMP4 on the proliferation and differentiation in SVZa neural stem cells

The neural stem cells in the anterior subventricular zone (SVZa) mainly generate the progenitors that will differentiate into neurons, and along a highly circumscribed migratory access Rostral migratory stream (RMS), they migrate to the olfactory bulbs (OB). To understand the effects of BMPs on SVZa neural stem cells, in this study BMP4 at various concentrations was used to induce SVZa neural stem cells, and the living cell labeling using BMP4 promotor conjugated with red fluorescence protein showed the expression of BMP4 dynamically. The results demonstrated that low BMP4 doses (1-5 ng/mL) promoted while high doses (10-100 ng/mL) inhibited the proliferation of SVZa neural stem cells, and BMP4 promotedneuron differentiation in the early stage (1-3 d), howeverm, it inhibited the neuron commitment after 4 d. Noggin, the antagonist of BMP4, blocked the physiological effects of BMP4. In OB, BMP4 is mainly to accelerate the progenitors to withdraw from the cell cycle and trigger the differentiation, and in RMS, it promotes the proliferation of committed progenitors and not differentiation, further in SVZa, BMP4 enhances astrocyte commitment.     

Does the FRN in brain potentials reflect motivational/affective consequence of outcome evaluation?

Electrophysiological studies have utilized event-related brain potentials (ERPs) to investigate neural processes related to the evaluation of the outcome of behavioral performance or to the evaluation of external feedback. The feedback-related negativity (FRN) in brain potentials has been shown to be sensitive to information indicating monetary loss or negative feedback. Since monetary loss usually indicates both the consequence of previous performance and the reward value of stimuli, it is controversial whether the FRN reflects the cognitive process of error detection per se and/or the motivational/affective process related to the subjective evaluation of the error. This study manipulated the motivational/affective significance of negative feedback by penalizing errors in a context-dependent way in a line judgment task. Participants could lose more money in the loss incentive condition or win less money in the win incentive condition if their subsequent judgment of line segments was less accurate, whereas they could receive performance feedback but without monetary incentive in the neutral condition. Results showed that the size of the FRN effect as well as the size of the P300 effect, as assessed by comparing brain responses to the error trials with the responses to the correct trials, increased linearly over the loss, neutral, and win conditions, suggesting that the FRN is sensitive to the motivational/affective evaluation of the performance outcome.     

焊接表面裂纹的工程评定

本文通过宽板拉伸试验,根据全面屈服准则和COD参量直接研完和评定了焊接构件中的表面裂纹。指出依据COD概念不能合理地评定和保证具有表面裂纹构件的安全性,而全面屈服准则是评定构件表面缺陷的有力工具。因为他不但保证构件具有不低于屈服限的强度,而且还具有良好的塑性。本文同时还详细地讨论了低温对表面裂纹极限尺寸的影响,     

QRS环前向电力增大235例分析

正常组:200例中QRS环前向电力增大+20~0者57例占28.30％,大于+30~0者5例占2.5％。异常组:235例中QRS环前向电力增大+20~0者74例占48％,大于+30~0者65例占27.6％。两组比较在大于+30‘以上有明显差异,表明QRS环前向电力增大至+30~0以上对左中隔支阻滞有临床意义。与疾病因素关系:冠心病84例中57例占24.25％,高血压病44例中28例占11.91％,糖尿病11例中6例占2.55％,较其它疾病检出率增高。运用心向量诊断左中隔支阻滞所致QRS环前向电力增大优越于心电图,按心向量诊断四项标准,运用心电图与心向量对照检查分析、结合临床判断较为稳妥。