求解粘弹性饱和土隧道频域响应的DQEM

用微分求积单元法研究了粘弹性饱和土隧道的频域响应问题.首先,基于饱和多孔介质混合物理论,分别建立了频域内隧道耦合系统中粘弹性饱和土和粘弹性衬砌的控制方程,给出了耦合系统的边界条件以及饱和土和衬砌连接面上满足的连接条件.其次,发展了求解该耦合系统的微分求积单元法,利用微分求积单元法,在频率域内对耦合系统的数学模型进行了离散,并利用Newton-Raphson迭代法得到了系统的数值解.最后,对耦合系统的频域响应进行了分析,考察了参数的影响,同时也验证了数值方法的有效性.     

Dual role of cAMP duringDictyostelium development

cAMP plays an essential role duringDictyostelium development both outside and inside the cell. Membrane-bound receptors and adenylyl cyclase are responsible for sensing and producing extracellular cAMP, whereas a phosphodiesterase is responsible for maintaining a low basal level. The molecular events underlying this type of hormone like signalling, which are now beginning to be deciphered, will be presented, in the light of cAMP analogue studies. The importance of intracellular cAMP for cell differentiation has been demonstrated by the central role of the cAMP dependent protein kinase. Mutants as well as strains obtained by reverse genetics will be reviewed which lead to our current understanding of the role of intracellular cAMP in the differentiation of both stalk and spore cells.     

基于ARM的海水总有机碳含量现场分析仪的硬件设计

针对海洋生态调查对海水总有机碳含量(TOC)的要求,研制了一种基于化学发光法检测海水 TOC值的现场分析仪。该仪器硬件基于SOC技术,采用ARM架构S3C2440微处理器,嵌入Windows CE操作系统。经过多次海试测量验证,该分析仪在保证测量精度的前提下,提高了测量速度,具有很好的现场应用性。     

Acyl fluorides as reactive mimics of aldehyde pheromones: hyperactivation and aphrodisiac inHeliothis virescens

Summary Substitution of fluorine for the aldehydic hydrogen provides behaviorally active, chemically reactive pheromone mimics. In male moths of the tobacco budwormHeliothis virescens, Z9–14:Acf and Z11–16:Acf cause hyperactivity and irreversible extension of the genitalia in over 80% of treated moths. In addition, a combination of the two components leads to 10–50% of the pairs involving one treated partner becoming locked in copula.Supported by NSF grant PCM-8112755 and DMB-8316931, by a Fellowship from the Alfred P. Sloan Foundation (1981–85), and by Teacher-Scholar Grant from the Camille and Henry Dreyfus Foundation (1981–86) to G.D.P. Address correspondence to G.D.P.     

Choline accumulation in isolated rat hepatocytes

Summary The accumulation of non-metabolized choline in isolated rat hepatocytes is concentrative in Na⁺ medium, whereas the accumulation does not exceed unity in a Li⁺ medium. Ouabain and 2,4-dinitrophenol inhibited the choline uptake. These results indicate that choline is taken up by rat hepatocytes via a Na⁺-and energy-dependent process, and choline oxidase is not directly connected with the choline transport system.     

benztropine类多巴胺转运蛋白配体的QSAR研究

利用Hansch方法，研究了37种benztropine类化合物diphenylmethoxy部位苯环取代基结构与其活性的定量关系，结果表明：苯环取代基的电性和体积等均是影响该类化合物与多巴胺转运蛋白亲和力的重要因素，所得到的benztropine类化合物diphenylmethoxy部位取代基的综合结构效应，对进一步研究该部位与多巴胺转运蛋白相互作用的电性和立体性质及设计新的多巴胺转运蛋白配体具有指导意义。     

基于Fizeau干涉仪的直接探测多普勒测风、激光雷达研究

回顾了基于Fizeau干涉仪的多普勒测风激光雷达的基本原理，在对测风雷达的主要参数说明的基础上，分析了多通道探测器的选择以及由于干涉仪圆形口径引起的通道间的能量修正系数问题，最后对基于Fizeau干涉仪多普勒测风激光雷达雷达系统的风速测量误差进行了数值模拟．结果显示，研制中的基于Fizeau干涉仪的多普勒测风激光雷达系统在5km以下范围内，风速测量误差可以达到0．56m／s（30s积分实际时间）．     

Isolation and characterization of soybean NBS analogs

Isolation of plant resistance genes is greatly helpful to crop resistance breeding and the insight of resistance mechanism. The cloned plant resistance genes are classified into four classes according to their putative structural domain, of which the majority possesses nucleotide-binding site (NBS) domain that consists of P-loop, kinase2a and kinase3a. The conservation of this domain affords the potential possibility of cloning the plant resistance genes, which is homology-based cloning technique. In the present study, the degenerate oligonucleotide primers were designed according to the tobaccoN andArabidopsis RPS2, and 358 clones were isolated from the genomic DNA of resistance soybean cultivar Kefengl, resistant to soybean mosaic virus, and 4 open-reading NBS analogs were finally characterized and designated asKNBS1, KNBS2, KNBS3 andKNBS4. Southern hybridization suggested that they were present with multicopy in the soybean genome;KNBS4 was mapped to F linkage group andKNBS2 co-located J linkage group with the SCAR marker ofRsa resistant to soybean mosaic virus by RFLP analysis. Northern analysis suggested thatKNBS2- related sequence was low and constitutively expressed in the root, stem and leaves of soybean. The detailed characterization of NBS analogs is very helpful to ultimately cloning the soybean resistance gene.     

基于DQEM的分层流体饱和热弹性多孔介质轴对称问题的动力响应分析

研究了分层不可压流体饱和热弹性多孔介质轴对称问题的动力响应问题,基于多孔介质理论(PMT),给出了该问题的数学模型.在空间域内采用微分求积单元法(DQEM)设置离散的控制微分方程、边界条件和连接条件,在时间域内采用二阶向后差分格式处理时间导数.在离散化的初始条件下,运用Newton-Raphson法进行迭代求解,得到各离散点处未知物理量的数值结果.研究表明:该方法有效、可靠,且具备精度较高、计算量较小、数值稳定等优点.