Cytosolic factors in mitochondrial protein import

In vitro import studies have confirmed the participation of cytosolic protein factors in the import of various precursor proteins into mitochondria. The requirement for extramitochondrial adenosine triphosphate for the import of a group of precursor proteins seems to be correlated with the chaperone activity of the cytosolic protein factors. One of the cytosolic protein factors is hsp70, which generally recognizes and binds unfolded proteins in the cytoplasm. Hsp70 keeps the newly synthesized mitochondrial precursor proteins in import-competent unfolded conformations. Another cytosolic protein factor that has been characterized is mitochondrial import stimulation factor (MSF), which seems to be specific to mitochondrial precursor proteins. MSF recognizes the mitochondrial precursor proteins, forms a complex with them and targets them to the receptors on the outer surface of mitochondria.     

大型海水淡化装置流场数值模拟及其优化

以往对提高海水淡化装置特别是多级闪发装置(MultiStage Flash MSF)效率的研究多局限于提高热效率的方面,或者是采用化学的方法,而忽视了从流体力学角度,通过改变闪发腔内流动情况来提高效率. 本文利用计算流体力学软件Phoenics 采用数值方法模拟闪发式海水淡化装置内的水流特性, 并分析闪发室内阻流板的设置对水流的湍流度与流动损失的影响,从而为闪发室的设计提供合理的依据.     

时域宽带矩阵空域滤波器设计方法

提出了一种基于FIR滤波器的时域宽带矩阵空域滤波器设计方法.首先,采用窄带矩阵空域滤波器优化设计方法,设计对应工作频带内各子带的恒定扇区响应空域滤波加权矩阵集.应用该矩阵集元素重构N个宽带基阵加权向量集,设计对应的N个恒定响应空域宽带FIR滤波器,进而构成时域宽带矩阵空域滤波器.该方法实现了对阵元接收宽带数据的时域矩阵空域预滤波,提高了系统的实时信号处理能力.计算机仿真和实验数据处理结果验证方法的有效性.