食管支架径向支撑性能

针对目前编织型食道支架支撑性研究存在的问题,完成了支架几何模型及有限元模型的创建、材料模型的选取以及边界条件的设置,提出了基于有限元分析的食管支架径向支撑力计算方法,并对不同头数、不同丝径、不同导程支架的径向支撑力进行分析.分析结果显示:头数越多,径向支撑力越大;丝径越大,径向支撑力越大;导程越大,径向支撑力越小.支撑...     

微孔结构血管支架的激光切割工艺

研究了切割微孔血管支架用激光的选择及相应参数的选取、激光切割对被加工材料的要求、喷嘴形状尺寸及辅助气体压力参数等影响切割质量的因素;探讨了切割质量的分析评价方法,分析了切割路径对切割效率的影响;通过正交试验法选择最佳切割参数;提出了面向微孔血管支架激光加工的完整工艺,并依据研究的工艺加工出便于载药的带有微孔结构的血管支架产品,支架表面的扫描电镜图观测验证了该工艺结果的正确性.     

主髂动脉硬化闭塞症的手术治疗

报道了48例主髂动脉闭塞症病人的手术治疗结果。行人造血管搭桥转流术31例，其中有8例同时行球囊导管扩张、动脉内膜剥成形或取栓术；导管动脉取栓扩张5例；动脉内膜剥脱、取栓3例；血管腔内支架置放9例。临床症状消失或好转42例，随访0.5-9年人造血血管通畅率90%。多普勒血流仪节段性测压踝/肱指数（ABI）对临床诊断、治疗和预后均有较高的价值，当ABI小于0.5时，应及时手术，挽救肢体，在确定治疗方案时，应根据病变部、分布和严重程度，施行不同的手术方法才能提高血管通畅率，得到良好的疗效。     

实验性下腔静脉可扩张性内支撑形态学研究

通过观察实验犬下腔静脉内放置可扩张性内支撑后血管的形态学变化，确定支撑的内皮化进程，以期为临床减少内支撑阻塞，合理应用抗凝剂提供组织学的依据。方法；在１４只杂种犬下脸静脉人放置金属内支撑，于术后１个月起，逐月取下腔静脉作光镜和电镜检查。     

Experimental Study on the Mechanical Properties of Novel Plate-knitted Composite Tracheal Stents

A new knitted composite artificial tracheal stent made of polyglactin(PGLA) and polypropylene (PP) filaments for reinforcement and regeneration of human trachea has been developed by plated-knitting technique on a small-diameter circular knitting machine. Both tensile and compressive tests were carried out to determine the Young's modulus and the critical pressure corresponding to crushing of the stent. The experimental results confirmed that the new type of knitted composite artificial stent is mechanically feasible.     

PDO血管内支架的制备及其径向压缩性能

以4种不同直径的聚对二氧环己酮(PDO)单丝为原料,采用手工编织的方法制备16种不同编织密度的血管内支架.对PDO单丝的力学性能、血管内支架的结构参数、径向压缩性能的测试方法和径向压缩性能进行试验研究.试验结果表明:采用PDO单丝手工编织的血管内支架的孔隙率符合选用要求;血管内支架的径向支撑力和弹性回复率随着单丝直径与编织密度的增加而增加,且单丝直径对血管内支架的径向压缩性能影响更显著.     

Current status of research and application in vascular stents

Cardiovascular diseases have been the leading cause of death in modern society. Using vascular stents to treat these coronary and peripheral artery diseases has been one of the most effective and rapidly adopted medical interventions. During the twenty-five years＇ development of vascular stents, revolutionary cardiovascular stents like drug eluting stents and endothelial progenitor cells capture stents have emerged. In this review, the evolution of vascular stents is summarized, aiming to provide a glimpse into the future of vascular stents. Advanced designs, focusing on the investigations of new substrates, new platforms, new drugs and new biomolecules are currently under evaluation with promising clinical studies. The concept of ＂time sequence functional stent＂ has been raised in this paper. It presents anti-proliferative properties in the first phase after implantation and subsequently support endothelialization. It also shows long-term inertness without release of toxic ions or toxic degradation products. The success of this concept is briefly presented with a clinical study in this model stents.     

移植肾动脉狭窄的支架治疗效果与安全性探讨

目的探讨移植肾动脉狭窄的支架治疗效果与安全性.方法1例肾移植术后的女性患者,2 a前采用移植肾动脉与髂内动脉远端行端-端吻合术,移植肾脏固定在右髂窝内.术后2 a发生移植肾动脉狭窄80%,狭窄性病变长度15 mm,接受了支架治疗.从左股动脉入路,应用Judkin 6F右冠指引导管,植入冠脉金属裸支架4.0 mm×18 ...     

浅谈北澄子河大桥钢管砼拱主桥施工

大桥为S255省道（高邮三 至江都港区段）的一座跨径80．6m的下承式钢管混凝土拱桥,刚性系梁为1．4m×1．8m预应力箱形梁,采用支架现浇方法施工。该桥横跨北澄子河,受地埋条件及通航影响,施工难度大。经过方案比选,钢管拱采用了简易支架整体吊装的方案,取得了显著的经济效益。     

生物可降解镁合金支架的扩张性能

介绍了生物可降解镁合金支架的应用背景和研究现状.应用有限元方法研究了镁合金支架的扩张过程.为了便于分析和比较,同时建立了具有相同几何模型的316L医用不锈钢支架,分别比较了它们在几何变形、应力分布、轴向缩短率、扩张速度等方面的差异性.结果显示,扩张镁合金支架比扩张不锈钢支架要容易得多.在扩张压力和扩张直径相同的前提下扩张镁合金支架和不锈钢支架,前者的扩张速度高于后者;前者的轴向缩短率小于后者;扩张到最大直径时,前者的最大Von Mises应力小于后者.有限元模拟对支架性能的评价和设计有一定指导意义.