排序方式: 共有6条查询结果,搜索用时 109 毫秒
1
1.
2.
Vargas F. Osuna A. Fernández-Rivas A. 《Cellular and molecular life sciences : CMLS》1996,52(3):225-229
The effects of adenosine triphosphate (ATP) on the renal vasculature of isolated kidneys from control, hyper- and hypothyroid rats were characterized. ATP responsiveness was evaluated in basal tone and in raised tone (phenylephrine 10–6 M) preparations. These responses were compared with those obtained with barium chloride or sodium nitroprusside (SNP), used respectively as nonreceptor agonists for vasoconstriction or vasodilation. In preparations at basal tone, ATP produced dose-related vasoconstriction, which was increased in hyperthyroid kidneys, and was severely attenuated in kidneys from hypothyroid rats. In raised tone preparations from control rats ATP produced a dual response: vasoconstriction at low doses, which declined with increasing doses to give way to vasodilator responses; biphasic responses were found in some kidneys. Hyperthroid kidneys showed increased pressor responses and a vasodilator response similar to those seen in kidneys from control rats. However, in hypothyroid kidneys the vasodilator response was abolished. The responses to barium chloride and to SNP were significantly increased and decreased in hyper- and hypothyroid kidneys, respectively; vasoconstrictor responses to SNP were also found in hypothyroid kidneys. Hence the abnormal responses to ATP observed in both thyroid dysfunctions may be partially explained by unspecific alterations in the contractile machinery of the renal vasculature in these kidneys. However, ATP responsiveness (vasoconstriction at low tone and vasodilation at raised tone) was more severely affected in hypothyroid kidneys, suggesting that purinergic (P2X and P2Y) receptor activity may be decreased in these organs. 相似文献
3.
为探讨儿童甲状腺功能亢进 (甲亢 )的外科治疗方法 ,回顾性分析了 18例 15岁以下甲亢实施手术治疗的临床资料 .结果本组无 1例死亡 .12例经 4月~ 5年随访 ,无并发症 ,无复发 .说明儿童甲亢手术治疗是一种安全、快速、有效的方法 ,但需严格掌握手术指征及预防并发症的发生 相似文献
4.
甲状腺功能亢进对血糖和胰岛素水平的影响 总被引:1,自引:0,他引:1
陈立波 《北华大学学报(自然科学版)》2000,1(1):39-40
目的 观察甲状腺功能亢进患者的糖代谢情况。方法 将38例甲状腺功能亢进患者及与患者性别、年龄相应的健康对照者16例,均进行空腹、餐后2h的血糖、胰岛素明显升高,与健康对照组比较均有显著差异(P〈0.01)。结论 甲亢患者有餐后高血糖、高胰岛素血症,存在胰岛素抵抗。 相似文献
5.
王丽杰 《内蒙古民族大学学报(自然科学版)》2014,(6):686-687
目的:观察益目胶囊治疗甲亢伴突眼的临床疗效.方法:将112例甲亢性突眼患者随机分为两组,治疗组和对照组,治疗组给予自制益目胶囊内服.对照组给予强的松片口服,30天为1疗程,两组均连续治疗3个疗程,观察两组治疗前后的症状改善情况.结果:治疗组有效率为83.9%,对照组为60.7%.结论:益目胶囊能有效改善甲亢性突眼的临床症状. 相似文献
6.
目的:探讨131Ⅰ治疗甲亢前后甲状腺功能的早期动态变化,缩小对治疗后甲亢危象的原因认识差距。方法:对40例接受131Ⅰ治疗的甲亢患者进行了5mo的随访观察,用放射免疫法测定了治疗前后不同时期血清甲状腺激素浓度并对测定结果进行统计学处理。结果:治疗前和治疗后1w内、1mo内各激素值无统计学意义(P>0.05),治疗后3~5mo内各激素值与较之上述3个时期均明显下降,且差别都有显著的统计学意义(P<0.01)。结论:甲亢131Ⅰ治疗有效、安全;大部分(77.5%)甲状腺功能于治疗后3~5mo恢复正常;在目前所用131Ⅰ剂量下治疗后不会因大量甲状状腺激素短时间内进入血中而致甲亢危象。 相似文献
1