Multiple Suppressive Effects of a Protein from Caesalpinia minax on Murine Melanoma Cells

IntroductionIn recent years,a great deal of attention hasfocused on finding potential anti- tumor agentsfrom natural sources[14 ] .A vast number ofpromising candidate molecules,especiallycomponents extracted from plants,have beenevaluated[59] .　 Herbs have a long history of use as Chinesetraditional medicine.Caesalpinia minax (C.minax) is a wild plantin Yunnan Province,China.The high level of ultraviolet radiation in thistropical province causes widespread skin diseases inthis area.Extract…     

塔拉倍半萜成分的研究

对塔拉枝叶的化学成分进行了研究.利用现代多种色谱技术从其乙醇提取物氯仿萃取部分分离得到7个倍半萜类化合物,利用波谱技术鉴定了它们的结构,分别为4(15)-eudesmene-1β,6α-diol(1)与ent-4(15)-eudesmene-1β,6α-diol(2)的混合物、4(15)-eudesmene-1β,5α-diol(3)、oplopanone(4)、(7R*)-opposit-4(15)-ene-1β,7-diol(5)、cloven-2β,9α-diol(6)和tricyclohumuladiol(7),所有化合物均为首次从该植物中分离得到.     

Antioxidant Activity In Vitro of Three Constituents from Caesalpinia sappan L

Antioxidant activities of the 95% ethanol extract from Caesalpinia sappan heartwood (ECS),pro-tosappanin A,protosappanin B,and brazilein were studied in vitro.The inhibition of the formation of malondialdehyde (MDA) and the scavenging of superoxide anions,hydrogen peroxide,and hydroxyl radicals were assayed.The experimental results show that all four substances had antioxidant activity in vitro but their capabilities differed for the different indicators.ECS,protosappanin A,and protosappanin B show more inhi-bition of MDA and scavenging of hydrogen peroxide,while brazilein shows more scavenging of hydroxyl radicals.All the samples show little scavenging of superoxide anions.     

刺果苏木（Caesalpinia cristal）化学成分的研究

从中国北部湾采集的剌果苏木(Caesalpinia cristal)中分离得到4个结晶化合物,通过 IR、~1H NMR,~(13)C NMR,MS以及元素分析等手段鉴定了它们的结构。本文报道(D)-4-O-甲基-肌-肌醇和24,26-甲基-3β-羟基-5-烯胆甾醇。前者是一种新化合物。     

Antioxidant Activity In Vitro of Three Constituents from Caesalpinia sappan L

Antioxidant activities of the 95% ethanol extract from Caesalpinia sappan heartwood （ECS）, protosappanin A, protosappanin B, and brazilein were studied in vitro. The inhibition of the formation of malondialdehyde （MDA） and the scavenging of superoxide anions, hydrogen peroxide, and hydroxyl radicals were assayed. The experimental results show that all four substances had antioxidant activity in vitro but their capabilities differed for the different indicators. ECS, protosappanin A, and protosappanin B show more inhibition of MDA and scavenging of hydrogen peroxide, while brazilein shows more scavenging of hydroxyl radicals. All the samples show little scavenging of superoxide anions.     

喙荚云实的化学成分研究

对喙荚云实Caesalpinia minax枝和叶的化学成分进行了研究.利用现代多种色谱技术从喙荚云实枝和叶的乙醇提取物中分离得到7个化合物,利用波谱技术鉴定了它们的结构,分别为S(+)-dehydrovomifoliol(1)、loliolide(2)、vomifoliol(3)、taraxerol(4)、3,13-dihydroxy-12-oleananone(5)、glutinol(6)、3β-hydroxysitost-5-en-7-one(7),化合物类型主要为倍半萜和三萜,所有化合物均为首次从喙荚云实中得到.     

中国云实属植物资源的调查研究

通过野外考察 ,查阅标本资料 ,搞清了中国云实属植物种类、地理分布及药用价值 ,为进一步开发利用中国云实属植物提供科学依据。