Science Letters： A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen

It has been proposed that activation of Toll-like receptors （TLRs） plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 （TLR2） ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen （HDM）. Mice were sensitized and challenged with Dermatophagoidesfarinae allergen （Der f）, and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid （BALF）. Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases.     

（BN）n及SiB（n-1）Nn（n=2-11）稳定结构的研究

利用遗传算法及Gastreich提出的经验势函数,研究了（BN）n（n=2-11）和SiBn-1Nn（n=2-11）团簇的可能稳定结构,对能量较低的异构体在HF/STO-3G水平进行优化,得到了（BN）n（n=2-11）和SiBn-1Nn（n=2-11）团簇稳定结构单环及线状结构,并进一步分析了单环的结构特征及相对稳定性。     

日本人的“ラち”、“そと”意识与日语的时态转换

从日本人的“ラち”、“そと”意识角度出发，通过对川端康成、志贺直哉的几部小说进行分析统计，探讨日语在描写过去的事件中，插入“内时态‘る’形”的条件和原因。分析发现当作者为了使作品更生动，或是作者与作品中人物产生“同感”时，或是表达作者的主观思想、评论时，往往发生时态的转换。     

Third-order optical nonlinearities for lanthanum (Ⅲ) complexes with 1,10-phenanthroline components

The nonlinear refractive indexes n 2 for the ethanol solutions of 1,10-phenanthroline (2.0×10 -3 mol·L -1), [bis(1,10-phenanthroline) lanthanum (Ⅲ)] nitrate (1.0×10 -3 mol·L -1), and [nitrato-fluoracil-bis (1,10-phenanthroline) lanthanum (Ⅲ)] nitrate (1.0×10 -3 mol·L -1) are first measured, the third-order nonlinear optical susceptibilities χ (3) and <γ> are calculated, and the mechanisms of the third-order optical nonlinearities enhanced by lanthanum (Ⅲ) are discussed preliminarily.     

用分光光度法研究二过碘酸合铜(Ⅲ)配离子氧化乙二胺的动力学

采用分光光度法研究了二过碘酸合铜（Ⅲ）氧化乙二胺的反应动力学及机理。结果表明,反应对Ｃｕ（Ⅲ）是准一级。准一级速率常数ｋｏｂｓ随乙二胺（ＥＤＡ）的浓度增大而增大,为正分数级,且１／ｋｏｂｓ对１／［ＥＤＡ］有较好的线性关系。ｋｏｂｓ随ＯＨ－［］的增大而增大;随ＩＯ－４［］的增大而减小。据此提出了包括前期平衡的反应机理,解释了实验现象,求得了速率控制步骤的速率常数。     

Ag（Ⅲ）络离子－尿素氧化还原引发丙烯腈聚合反应的研究

本文采用水相沉淀聚合法研究了二过碘酸合银（Ⅲ）－尿素氧化还原引发体系在碱性介质中引发丙烯腈聚合反应，测得了各种因素对聚合反应速率、聚合物分子量的影响，并探讨了引发机理。     

清中后期社会历史文化心态的展现——以小说《荡寇志》为例

《荡寇志》是清中后期保守士人面对西潮涌入、传统文化失落的集体性情感反应的产物,小说作者俞万春以捍卫中国传统文化的基本价值为己任,担负起了文化卫道的使命。但残酷的现实却撕碎了他加强君权、帝制,肃清内乱来重振国威的卫道美梦,小说《荡寇志》便展示了这一特定历史时期各种社会变革思潮下的社会历史文化心态。     

Description of rotational properties of the superheavy nucleus ^256,258,260Rf by projected shell model

Band structure of the Z = 104 nucleus 256Rf has been a recent research focus in nuclear physics. We performed projected shell model calculations for this and some other neighboring Rf isotopes. Specifically, we studied rotational properties of these nuclei and showed that variations in dynamic moment of inertia were sensitive to single-particle structures, which may be useful information for locating the anticipated island of stability. Electromagnetic transition properties were also calculated, and measurable quantities were predicted for further experimental test.     

5-硝基水杨醛缩乙二胺双希夫碱钴(Ⅲ)配合物的合成、晶体结构及热稳定性研究

利用水热法合成了一例新的超分子配合物——5-硝基水杨醛缩乙二胺双希夫碱钴(Ⅲ)配合物.通过元素分析、红外光谱和X-射线单晶衍射等手段对其组成、结构进行了研究,并对合成条件进行了探讨.结果表明,配体采用四齿螯合的方式与金属钴离子配位,配合物结构单元之间通过分子间氢键构筑得到了配合物的超分子网络结构.热重分析表明,配合物具有良好的热稳定性.