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应用草酸-焦锑酸盐结合的沉淀技术研究了在不同Ca^2 浓度条件下斑节对虾光感受器细胞胞内储存的Ca^2 的变化,电镜观察表明:在高钙溶液培育后,细胞内的多囊体、色素颗粒、板膜体中都存在大量的焦锑酸钙沉淀的黑色颗粒,线粒体中则无;在生理溶液培育后,线粒体中出现沉淀,而其他Ca^2 储存器中焦锑酸钙沉淀的黑色颗粒则大量减少,低钙溶液培育后焦锑酸钙沉淀的黑色颗粒情况与生理溶液条件下的相似,研究证实光感受器细胞内储存的Ca^2 受到胞外Ca^2 浓度的影响。 相似文献
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Allingham JS Klenchin VA Rayment I 《Cellular and molecular life sciences : CMLS》2006,63(18):2119-2134
Natural small-molecule inhibitors of actin cytoskeleton dynamics have long been recognized as valuable molecular probes for
dissecting complex mechanisms of cellular function. More recently, their potential use as chemotherapeutic drugs has become
a focus of scientific investigation. The primary focus of this review is the molecular mechanism by which different actin-targeting
natural products function, with an emphasis on structural considerations of toxins for which high-resolution structural information
of their interaction with actin is available. By comparing the molecular interactions made by different toxin families with
actin, the structural themes of those that alter filament dynamics in similar ways can be understood. This provides a framework
for novel synthetic-compound designs with tailored functional properties that could be applied in both research and clinical
settings.
Received 6 April 2006; received after revision 31 May 2006; accepted 19 June 2006 相似文献
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用NH4F作掩蔽剂,甲基红做指示剂,用酸碱滴定法测HCl-FeCl3混合试液中的HCl结果满意。 相似文献
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