西安城市周边地带的界定

在定义城市周边地带的基础上，分析了城市周边地带城市化特征．根据西安市城市空间结构现状，利用专家打分法确定了西安市各区县隐性城市化调整系数，提出计算其城市化率的公式．根据计算结果初步界定了西安城市周边地带范围．     

偶应力两层流体通过狭窄管腔时外围层的粘度效应

本文讨论了偶应力两层流体通过带有柔和狭窄的刚圆管时的流动特性,导出了速度、流量、阻抗和壁面最大剪应力的解析式,考察了外围层粘度和厚度的效应,并作了数值计算;是对单层偶应力流体狭窄流动及两层牛顿流体(粘度不同)狭窄流动的推广。     

合理营养在延缓和消除运动性疲劳中的重要作用

从探讨运动性疲劳产生的原理入手,阐述了六大营养素在运动中促进疲劳消除的各自作用,并针对不同运动项目提出了如何合理调配营养,以利于加速训练或比赛中体力的恢复、提高训练效果或运动成绩的建议和措施.     

电针对佐剂性关节炎大鼠炎症局部阿片肽基因表达的影响

以佐剂性关节炎大鼠为炎症痛模型，选择悬钟，昆仑穴位，采用原位杂交组织化学方法，观察电针（ＥＡ）对大鼠炎症局部阿片肽前体物质前阿黑皮素（ＰＯＭＣ）和前脑啡肽原（ＰＥＮＫ）ｍＲＮＡ的表达，结果ＥＡ可以促进炎症局部免疫细胞中ＰＯＭＣ和ＰＥＮＫ ｍＲＮＡ的表达，使阿片肽的合成和释放增加，以实现外周炎症局部的镇痛作用。     

数字在屏幕显示控制核的设计与FPGA实现

设计了一种数字在屏幕显示(On Screen Display,OSD)控制核,在水平和垂直扫描信号同步下,根据用户软件设置字符及位图的显示属性,合成OSD图像数据,与输入视频叠加显示.利用现场可编程门阵列(Fied Programmable Gate Array,FPGA)进行验证和性能测试,并通过温度实验,工作稳定可靠.将其应用于一款军用液晶显示器(Liquid Crystal Display,LCD),解决了实际问题.该OSD控制核的特点在于把基于字符和位图的两种OSD图像生成方法融合在一起,功能得到增强,生成了图文信息丰富的OSD图像,串、并行两种用户接口提高了系统兼容性.     

非小细胞肺癌外周血有核细胞miRNA表达特点研究

miRNA在非小细胞肺癌的发生发展中发挥重要作用,为了解非小细胞肺癌患者外周血有核细胞的miRNA表达特征及其作用,采用第二代高通量测序技术对7例非小细胞肺癌患者和7例对照的外周血有核细胞miRNA表达水平进行检测,比较非小细胞肺癌患者与对照的外周血有核细胞miRNA表达特征,分析两者miRNA表达水平差异情况,共鉴定出非小细胞肺癌患者与对照的外周血有核细胞中有显著表达差异的miRNA 209种,其中肺癌样本miRNA表达上调的有138种,表达下调的有71种.研究结果显示非小细胞肺癌患者与对照样本的外周血有核细胞中miRNA表达具有显著差异,其中部分已被证实参与肿瘤发生、发展等过程.     

氦氖激光治疗与氦氖激光配合针灸治疗周围性面瘫疗效观察

观察氦氖激光配合针灸疗法对周围性面瘫患者的治疗效果,寻求最行之有效的治疗方法;探索叠加法治疗的优势,为治疗周围性面瘫的进一步发展提供理论数据.选择病程在急性期[(1～7) d内)]符合纳入标准的患者40例,随机分为治疗组、对照组各20例,对照组采用氦氖激光治疗仪照射单项治疗方法,治疗组在常规氦氖激光单项疗法的同时加用针灸治疗,分别于治疗14 d后和21 d后评定疗效.以抬额、皱眉、闭眼、耸鼻、患侧面肌肌力、鼻唇沟、鼓腮、示齿、吹口哨、降下唇等体征的程度变化为观察指标,对两组患者治疗前后的病情均予以评分及分级,运用spss13.0软件进行统计学分析,对临床资料和疗效进行χ2分析,对计量资料进行T检验.在用两种方法治疗14 d及21 d后,两组均见明显缓解症状,较显著的改善患者面神经功能评分,前后差值比较有统计学意义(P<0.01),且治疗组在促进患者面神经功能恢复方面优于对照组.经统计学分析,治疗14 d后治疗组总有效率为80%,对照组总有效率为60%;21 d后治疗组总有效率为95%,痊愈率为80%,对照组总有效率为90%,痊愈率为50%,两组比较有显著性差异 (P<0.05),治疗组疗效优于对照组.说明:(1)氖激光照射单项疗法和针灸与氦氖激光配合治疗的方法对周围性面瘫均有治疗作用.(2)针灸与氦氖激光配合治疗的方法与氦氖激光照射单项疗法相比,在改善患者面神经功能方面具有显著优势,能增强疗效、缩短病程、提高患者生活质量,同时减少副作用、改善预后,是周围性面瘫的优选治疗手段.     

周边缝拱坝应力的弹性有限条元分析

本文应用壳体理论和有限条元法解周边缝拱坝的坝体变位与应力，导得坝体条元的刚度矩阵及等效结线荷载，编制了计算机程序和计算实例。     

Myelin sheaths: glycoproteins involved in their formation,maintenance and degeneration

Myelin sheaths are formed around axons by extending, biochemically modifying and spiraling plasma membranes of Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS). Because glycoproteins are prominent components of plasma membranes, it is not surprising that they have important roles in the formation, maintenance and degeneration of myelin sheaths. The emphasis in this review is on four integral membrane glycoproteins. Two of them, protein zero (P0) and peripheral myelin protein-22 (PMP-22), are components of compact PNS myelin. The other two are preferentially localized in membranes of sheaths that are distinct from compact myelin. One is the myelin-associated glycoprotein, which is localized at the inside of sheaths where it functions in glia-axon interactions in both the PNS and CNS. The other is the myelin-oligodendrocyte glycoprotein, which is preferentially localized on the outside of CNS myelin sheaths and appears to be an important target antigen in autoimmune demyelinating diseases such as multiple sclerosis. Received 8 April 2002; received after revision 13 May 2002; accepted 22 May 2002     

Genistein inhibits human TNF-α-induced porcine endothelial cell adhesiveness for human monocytes and natural killer cells

Cellular immune response is a major barrier to xenotransplantation. Human tumor necrosis factor-α (hTNF-α) possesses cross-species activity and directly amplifies the immune rejection via the upregulation of adhesion molecules on porcine endothelium. We investigated the role of protein tyrosine phosphorylation in the induction of expression of E-sclectin and vascular cell adhesion molecule-1 (VCAM-1), and the augmentation of adhesion of human peripheral blood monocytes (PBMo) and natural killer cells (PBNK), after rhTNF-α-stimulation of porcine aortic endothelial cells (PAEC) in vitro, rhTNF-α-increased adhesiveness of PAEC for both PBMo and PBNK was dose-dependently reduced by pretreatment of PAEC with the selective protein tyrosine kinase (PTK) inhibitor genistein. The inhibitory effect occurred at the early time of PAEC activation triggered by rhTNF-α, and was completely reversible. PTK activity assay indicated that genistein also suppressed rhTNF-α stimulated activation of protein tyrosine kinases (PTKs) in PAEC in a dose-dependent manner. Flow cytometric analysis showed that genistein inhibited the upregulation of E-selectin and VCAM-1 by rhTNF-α. These results suggest that PTKs may regulate the expression of E-selectin and VCAM-1 on PAEC and the adherence of PBMo and PBNK induced by rhTNF-α. Moreover, dietary genistein, used as an adhesion antagonist, may contribute to managing the cell-mediated rejection in the clinical application.