行政合同概念之检讨与重塑

行政合同概念的界定是研究进而规范行政合同的基础。长期以来,学界关于行政合同概念的界定多有分歧,主要表现在行政合同主体的范围、行政合同法律关系的归属、行政合同主体的意思自治程度、行政合同主体的地位等方面。从行政合同的主体要素、内容要素、意思要素、目的要素、地位要素和形式要素等方面进行综合分析,可以对行政合同作如下界定,即所谓"行政合同",是指为了公共目的,行政主体与行政相对人依法设立、变更、终止行政法上权利义务关系的协议及以之为载体实施行政行为的方式。     

SET domain protein lysine methyltransferases: Structure, specificity and catalysis

Site- and state-specific lysine methylation of histones is catalyzed by a family of proteins that contain the evolutionarily conserved SET domain and plays a fundamental role in epigenetic regulation of gene activation and silencing in all eukaryotes. The recently determined three-dimensional structures of the SET domains from chromosomal proteins reveal that the core SET domain structure contains a two-domain architecture, consisting of a conserved anti-parallel β-barrel and a structurally variable insert that surround a unusual knot-like structure that comprises the enzyme active site. These structures of the SET domains, either in the free state or when bound to cofactor S-adenosyl-L-homocysteine and/or histone peptide, mimicking an enzyme/cofactor/substrate complex, further yield the structural insights into the molecular basis of the substrate specificity, methylation multiplicity and the catalytic mechanism of histone lysine methylation. Received 10 June 2006; accepted 22 August 2006     

蓬园100号锦橙少籽原因初探

蓬园100号锦橙品质好、种子少。细胞学观察染色体数目为2n=18。其少籽原因不是染色体数目异常,而是减数分裂中大量小孢子母细胞之间染色质穿壁导致遗传物质的分配不均和减数分裂异常,产生大量败育花粉粒所致。单核期是小孢子败育的主要时期。     

The effect of cycloheximide on nuclear uH2A content

Summary The effect of intraperitonal cycloheximide administration on acid-soluble rat liver chromatin proteins has been investigated by electrophoresis in acetic acid-urea polyacrylamide gels. A nonhistone protein, which migrates between oxidized histone H3 and histone H1 has been found tobe increased in amount following cycloheximide treatment. This protein seems to be identical with semihistone protein H24 (uH2A). A possible relationship of uH2A to the inhibition of rRNA synthesis is discussed.This work was supported by the Turkish Scientific and Technical Research Council (TUBITAK) Project No. TAG 339     

X染色质体在正常人体细胞中出现概率的研究

本文采用X染色质的鉴别方法 ,研究了部分人群正常体细胞中X染色质体的出现概率 .结果表明　　三个实验群体的X染色质体的概率分别为 35 .2 1± 6 .6 2 %、33 .0 4± 9.33 %、2 6 .84± 8.5 8% ,它们之间差异不显　　著 (P >0 .0 5 ) .说明X染色质体在不同个体的相同组织中出现的情况有异 ,但差异不显著     

成人礼的复兴与重塑

成人礼在当今社会仍有其积极的作用。大力复兴成人礼，不仅要注重形式创新，更要加强内涵建设，以期更好地发挥成人礼的育人功能和社会价值。     

Interaction of lipid transfer protein with plasma lipoproteins and cell membranes

Summary The hydrophobic lipid components of lipoproteins, cholesteryl ester and triglyceride, are transferred between all lipoproteins by a specific plasma glycoprotein, termed lipid transfer protein (LTP). LTP facilitates lipid transfer by an exchange process in which cholesteryl ester and triglyceride compete for transfer. Thus, LTP promotes remodeling of the lipoprotein structure, and plays an important role in the intravascular metabolism of these particles and in the lipoprotein-dependent pathways of cholesterol clearance from cells. The properties of LTP, its mechanisms of action, its roles in lipoprotein metabolism, and its modes of regulation are reviewed along with recent data that suggest a possible role for this protein in directly modifying cellular lipid composition.