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南非作家南丁·戈迪默认为:"个人面临着持续的恐怖,是20世纪作家经验的核心。"她从残酷的种族隔离政策时期人的存在入手,深入发掘人的复杂性、多重性。"人是从自我到自我的行走",她的长篇《无人伴随我》对人的存在有着多种真实描述。她几部重要的长篇也显现出对历史的深度介入和伟大的人道主义情怀。 相似文献
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Reconstruction of linkage maps in the distorted segregation populations of backcross, doubled haploid and recombinant inbred lines 总被引:1,自引:0,他引:1
ZHU ChengSong WANG FuHua WANG JianFei LI GuangJun ZHANG HongSheng ZHANG YuanMing 《科学通报(英文版)》2007,52(12):1648-1653
Non-Mendelian segregation of markers, known as distorted segregation, is a common biological phenomenon. Although segregation distortion affects the estimation of map distances and the results of quantitative trait loci (QTL) mapping, the effects of distorted markers are often ignored in the construction of linkage maps and in QTL mapping. Recently, we have developed a multipoint method via a Hidden Markov chain method to reconstruct linkage maps in an F2 population that corrects for bias of map distances between distorted markers. In this article, the method is extended to cover backcross, doubled haploid and recombinant inbred line (RIL) populations. The results from simulated experiments show that: (1) the degree that two linked segregation distortion loci (SDL) affect the estimation of map distances increases as SDL heritability and interval length between adjacent markers increase, whereas sample size has little effect on the bias; (2) two linked SDL result in the underesti- mation of linkage distances for most cases, overestimation for an additive model with opposite additive effects, and unbiased estimation for an epistatic model with negative additive-by-additive effects; (3) the proposed method can obtain the unbiased estimation of linkage distance. This new method was applied to a rice RIL population with severely distorted segregation to reconstruct the linkage maps, and a bootstrap method was used to obtain 95% confidence intervals of map distances. The results from real data analysis further demonstrate the utility of our method, which provides a foundation for the inheritance analysis of quantitative and viability traits. 相似文献
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“我为反对白人统治而斗争,也为反对黑人统治而斗争.我珍视有一个民主和自由社会的理想,在这个社会里。人人和睦相处,机会均等,我为这个理想而活着,并希望实现这个理想。、但是如果需要,我也准备为这个理想而死。” 相似文献
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著名南非女作家纳丁.戈迪默在多年的写作生涯中,始终坚持把把公共关怀与文学创作结合起来,从未放弃对南非社会和南非人的深切关注。无论是在种族隔离时期的南非,新旧政权交替时期的南非,还是在种族隔离结束后的新南非,她从未停止创作以南非为背景,以南非人为主人公的小说。她用自己的实际行动向世人证明———知识分子从来就不是躲在象牙塔里的空谈者。 相似文献
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贾付强 《贵州师范大学学报(社会科学版)》2015,(2):66-71
南非种族隔离制度的终结作为一种社会历史结果是各种力量"合力"的产物:美苏冷战的终结与国际社会对南非的制裁在国际体系层面上推动了南非种族隔离制度的终结;种族隔离制度的内在矛盾与非白人群体的斗争在国家层面上推动了南非种族隔离制度的终结;而南非总统德克勒克与黑人领袖纳尔逊·曼德拉在个人层面上推动了南非种族隔离制度的终结。 相似文献