水溶性羧甲基壳多糖在化妆品上的应用

甲壳素和壳多糖可以通过化学变性和修饰制成水溶性的羧甲基壳多糖，介绍了羧甲基壳多糖用在化妆品成分中的各种性能，如它的保湿性能；pH值和热稳定性；与乙醇的复配性；与表面活性剂的配伍性；其他化妆品组分的配伍性和皮肤安全性等。由于羧甲基壳多糖来源丰富、价值便宜、保湿效果良好、性能稳定、安全无毒，因此它在化妆品领域将有着巨大的开发潜力和应用价值。     

脱乙酰壳多糖的荧光特性研究

研究了脱乙酰壳多糖固体膜及乙酸水溶液的荧光特性，考察了实验条件对荧光发射的影响．初步提出了脱乙酰壳多糖的荧光发射机制，发现分子内氢键和配位作用对脱乙酰壳多糖的荧光发射影响较大     

脱乙酰壳多糖的絮凝作用研究

对脱乙酰多糖的絮凝特征作了研究．实验结果表明，脱乙酰壳聚糖属于阳离子型絮剂，用量过多则产生絮凝恶化现象．它适合于酸性和中性的水和废水处理．温度升高和静置沉降时间延长有利于提高絮凝效果，电解质则对絮凝效果有影响．     

钯在脱乙酰壳多糖化学修饰电极上的电化学行为及分析应用

提出用脱乙酰壳多糖化学修饰电极为工作电极，阳极溶出伏安法测定痕量钯。在ｐＨ＝２的ＫＣｌ－ＨＣｌ底液中，＋０．０Ｖ富集２ｍｉｎ，以０．１Ｖ／ｓ扫速阳极溶出，峰电位在０．６７Ｖ（ｖｓ／ＳＣＥ），Ｐｄ在０．０７５￣９．９ｍｇ／Ｌ范围内与峰高呈良好的线性关系，相关系数ｒ＝０．９９９３。在富集１０ｍｉｎ时，可检测１．５μｇ／Ｌ Ｐｄ，大大提高了测定灵敏度。样品测定结果满意。同时研究了该体系的电化学性质和电极     

我国“人造皮肤”开始临床试验

由第三军医大学大坪医院野战外科研究所皮肤科主任伍津津教授研究的人造皮肤——复方壳多糖组织工程皮肤,在通过了国家药品与生物制品检定所的产品质量检测后,日前已开始在中国医学科学院皮肤病研究所、四川大学华西医院等7     

复方壳多糖组织工程皮肤的应用与推广

由第三军医大学大坪医院野战外科研究所研制的复方壳多糖组织工程皮肤具有表皮和真皮双层结构,含有角质形成细胞和成纤维细胞,组织结构接近天然皮肤。）物理特性良好,有一定的弹性和韧性,可任意移动、剪切、随意缝合,适合手术需要,具有很强的抗感染能力。适合于治疗大面积烧烫伤、慢性难愈性溃疡（糖尿病性溃疡、褥疮及静脉性溃疡）、疤痕疙瘩切除后的皮肤缺损,其市场前景巨大。     

Research of the Mechanism of Enhancing Biological Treatment by Chitosan

Chitosan of different molecular weight （M. W. ） was added into SBR bioreactor to treat domestic wastewater. From comparison of treatment efficiency, sludge activity, sludge structure etc., we revealed the mechanism that chitosan enhanced the biological treatment function of activated sludge. The results proved that, chitosan is certain to restrain the reaction of activated sludge, but it do improve the structure of sludge floes and increase the treatment efficiency of activated sludge. The bigger the M. W. of chitosan is, the better the efficiency of enhancing biological treatment can be.     

In Vitro Cytotoxicity and Protein Drug Release Properties of Chitosan/Heparin Mlcrospheres

Chitosan/heparin microspheres were prepared using the water-in-oil emulsification solvent evaporation technique. The microsphere diameters were controlled by selecting the fabrication process parameters. Scanning electron micrographs showed that the chitosan/heparin microspheres were regular and the surface morphology was smooth. Fourier transform infrared showed that the chitosan amino groups reacted with heparin carboxylic groups to form acylamides in the microspheres. Analysis of the microsphere cytotoxicity showed that they had no cytotoxic effect and behaved very similar to the negative control （polystyrene）. To analyze the protein drug release profiles of the microspheres, bovine serum albumin was loaded as a model drug into the microspheres and released in vitro. Marked retardation was observed in the BSA release profiles. The results show that chitosan/heparin microspheres may provide a useful controlled release protein drug system for used in pharmaceutics.     

用皮皮虾制壳多糖的土法生产方法

介绍了用皮皮虾制甲壳质和壳多糖的土法生产工艺过程及简单设备。     

蛋白双酶（胰蛋白酶─木瓜蛋白酶）的固定化研究

以脱乙酰壳多糖为载体，戊二醛为交联剂，对胰蛋白酶和木瓜蛋白酶的固定化条件及固定化双酶的动力学性质进行研究．实验对比了交联剂的用量、交联的ｐＨ值、温度及载体与酶的比例等因素对固定化的影响．确定了固定化双酶的催化特性：最适ｐＨ７．５～８．１，最适温度是６０℃，Ｋｍ值是０．５２ｍｇ／ｍｌ，并对固定化双酶的热稳定性、固定化双酶的活性与固定化单酶的活性进行了比较．