Science Letters： A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen

It has been proposed that activation of Toll-like receptors （TLRs） plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 （TLR2） ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen （HDM）. Mice were sensitized and challenged with Dermatophagoidesfarinae allergen （Der f）, and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid （BALF）. Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases.     

（BN）n及SiB（n-1）Nn（n=2-11）稳定结构的研究

利用遗传算法及Gastreich提出的经验势函数,研究了（BN）n（n=2-11）和SiBn-1Nn（n=2-11）团簇的可能稳定结构,对能量较低的异构体在HF/STO-3G水平进行优化,得到了（BN）n（n=2-11）和SiBn-1Nn（n=2-11）团簇稳定结构单环及线状结构,并进一步分析了单环的结构特征及相对稳定性。     

Face Recognition Based on Support Vector Machine and Nearest Neighbor Classifier

Support vector machine (SVM), as a novel approach in pattern recognition, has demonstrated a success in face detection and face recognition. In this paper, a face recognition approach based on the SVM classifier with the nearest neighbor classifier (NNC) is proposed. The principal component analysis (PCA) is used to reduce the dimension and extract features. Then one-against-all stratedy is used to train the SVM classifiers. At the testing stage, we propose an al-     

日本人的“ラち”、“そと”意识与日语的时态转换

从日本人的“ラち”、“そと”意识角度出发，通过对川端康成、志贺直哉的几部小说进行分析统计，探讨日语在描写过去的事件中，插入“内时态‘る’形”的条件和原因。分析发现当作者为了使作品更生动，或是作者与作品中人物产生“同感”时，或是表达作者的主观思想、评论时，往往发生时态的转换。     

互联电网低频振荡产生的机理及其抑制措施

总结了电力系统低频振荡的国内外现状,并在分析了电力系统低频振荡的数学模型的基础上,得出用PSS来抑制低频振荡的有效性,同时指出随着FACTS技术的发展,今后协调PSS和FACTS各个控制器之间的控制作用是彻底解决低频振荡问题的关键.     

某些特殊函数族支撑点的性质

本文研究了GL函数族和负实系数单叶函数族SR-支撑点的性质，得到了GL函数族支撑点的映照性质，并且获得了负实系数单叶函数族SR-的支撑点的形式．     

简评战后日本对中国的赔偿与援助问题

二战后中国政府放弃对日本的赔偿要求，日本政府对华援助是中日两国关系中的重大事件，这两个事件对日本和中国的现代化建设、对中日两国友好关系的发展，都起到了重要的促进作用。但是，日本政府对华援助则有许多自身考虑的因素。     

一种基于可变支持度的缺省规则挖掘算法

Rough集方法提供了一种新的处理不精确、不完全与不相容知识的数学工具. MDRBR算法通过规则支持度进行约束,可有效提高缺省规则的挖掘效率.但MDRBR采用单一的规则支持度约束,使得当规则支持度较小时,挖掘出大量的缺省规则,而当规则支持度较大时,一些重要的小概率分布对象对应的缺省规则被过滤掉.为此,提出了一种基于可变支持度的缺省规则挖掘算法--MDRBVSM,可有效地改进MDRBR等传统算法存在的缺陷.实验结果表明,该算法可有效地过滤噪声、提高规则的挖掘效率.     

清中后期社会历史文化心态的展现——以小说《荡寇志》为例

《荡寇志》是清中后期保守士人面对西潮涌入、传统文化失落的集体性情感反应的产物,小说作者俞万春以捍卫中国传统文化的基本价值为己任,担负起了文化卫道的使命。但残酷的现实却撕碎了他加强君权、帝制,肃清内乱来重振国威的卫道美梦,小说《荡寇志》便展示了这一特定历史时期各种社会变革思潮下的社会历史文化心态。     

Description of rotational properties of the superheavy nucleus ^256,258,260Rf by projected shell model

Band structure of the Z = 104 nucleus 256Rf has been a recent research focus in nuclear physics. We performed projected shell model calculations for this and some other neighboring Rf isotopes. Specifically, we studied rotational properties of these nuclei and showed that variations in dynamic moment of inertia were sensitive to single-particle structures, which may be useful information for locating the anticipated island of stability. Electromagnetic transition properties were also calculated, and measurable quantities were predicted for further experimental test.