数字几何体模仿真呼吸运动

仿真在补偿呼吸运动的PET/CT成像研究中起着非常重要的作用。许多方法被开发出来用于仿真呼吸运动。然而,它们在使用中存在一些局限性,例如操作者的干预,花费太高或者是仿真时间太长等。提出一种新的简单方法,用GATE软件包来实现呼吸运动的仿真。GATE不仅在SPECT/PET仿真,而且在不同的模型仿真构建方面也提供了非常强大的功能。根据呼吸运动,在GATE的配置中就可以确定体模运动的特征。GATE可以生成象柱,球和椭圆等形状的几何体模。组合体模的运动特征和形状就可以仿真呼吸运动。仿真的结果表明,在开发和评估SPECT/PET补偿呼吸运动技术时,GATE产生的运动体模,提供了一种可选的方法用于呼吸运动的仿真。这种方法与传统方法相比,运算量小,体模设置简单。

Abstract：

Simulation plays very important role in the research of compensation respiratory motion in PET/CT imaging. Many approaches were developed to simulate respiratory motion. However,they have some limitations on operator intervention,much cost or time consuming in study. A new simple approach for respiratory motion simulation was proposed by using GATE （Geant4 Application Tomography Emission） software packages. GATE provides very strong functions to simulate not only SPECT/PET,but also different phantom construction. Phantom motion characteristics can be determined in GATE configuration in terms of respiratory motion. Geometric phantom were generated by GATE including the shape of cylinder,sphere and ellipse. Combination of the characteristics of phantom motion and shape may simulate respiratory motion. The simulation results demonstrate that the phantom generated by GATE may provide as one alternative useful method of simulating respiratory motion for the development and the assessment of respiratory motion compensation in SPECT/PET imaging. This approach has the features of less computational simulation and phantom setting up simply comparing with conventional phantoms.