常规电教媒体的现状及对策

常规电教媒体在我国的教育教学改革过程中曾经发挥过积极的作用。随着科技的进步与发展，常规电教媒体日渐被冷落、遗忘；但常规电教媒体的优势仍然存在，只要采取相应的对策，常规电教媒体在我国教育事业的发展过程中仍可发挥出巨大的作用。     

用遗传算法解决一类模糊流水车间调度问题

对同时考虑模糊加工时间和模糊交货期的模糊流水车间调度问题进行了研究 ,模糊加工时间用三角模糊数来表示 ,模糊交货期用梯形模糊数来表示。应用遗传算法搜索最优排序 ,在适应度函数处理中引入模糊数处理方法 ,以平均满意度最大作为优化目标。最后给出了实验结果和结论     

玉米候选抗病相关基因片段的克隆

根据已经克隆的植物抗病基因和候选抗病基因的保守序列P-loop、Kinase-2及GLPLAL设计一系列简并引物，利用同源序列扩增法，对玉米的基因组DNA进行PCR扩增，并对5个扩增产物的克隆进行测序．测序结果在Gen—Bank内进行BLAST检索，发现A9克隆序列与玉米BAC库中的206C17克隆的部分序列有很高的相似性，并且距离GenBank内注册的玉米抗锈病基因rpl位点中的rpl-3基因、rpl-4基因分别约有66Kb、20Kb，且A9克隆序列在玉米基因组中是单拷贝的．这为玉米抗锈病性状的分子标记辅助选择和抗锈病基因的克隆奠定了良好的基础。     

低温热水地板辐射采暖在工程中的应用

简要介绍了低温热水地板辐射采暖的施工工艺以及施工中的注意事项。     

科普的系统化

科普是一项系统工程，科普系统是由科普主体、科普内容、科普媒介、科普受体等要素组成。科普工作者应将各要素有机地组织起来，针对不同地区的特点运用相应的科普手段和方法并进行有效的科普工作。     

阻抑动力学分光光度法测定痕量碘

研究了在稀硫酸介质中,痕量碘离子对亚硝酸根催化溴酸钾氧化百里香酚蓝的阻抑作用,建立了测定痕量碘离子的阻抑动力学光度分析的新方法.测定碘离子的线性范围为:0～0.32μg/mL,检出限为8.96×10-8g/mL.用于药品中的微量碘的测定,结果满意.     

光纤Bragg光栅横向负载敏感特性的实验研究

对光纤Bragg光栅的横向负载敏感特性进行了实验研究 .利用光纤中的应力双折射效应 ,使光纤光栅横向受压 ,产生谐振波长分裂 .通过实验研究得到了良好的谐振波长分裂与横向负载的关系曲线 ;在此基础上 ,进行了波长寻址的多点横向负载分布测量的初步探索 ,完成了两光栅同时传感的实验研究 .     

Gravity modes as a way to distinguish between hydrogen- and helium-burning red giant stars

Red giants are evolved stars that have exhausted the supply of hydrogen in their cores and instead burn hydrogen in a surrounding shell. Once a red giant is sufficiently evolved, the helium in the core also undergoes fusion. Outstanding issues in our understanding of red giants include uncertainties in the amount of mass lost at the surface before helium ignition and the amount of internal mixing from rotation and other processes. Progress is hampered by our inability to distinguish between red giants burning helium in the core and those still only burning hydrogen in a shell. Asteroseismology offers a way forward, being a powerful tool for probing the internal structures of stars using their natural oscillation frequencies. Here we report observations of gravity-mode period spacings in red giants that permit a distinction between evolutionary stages to be made. We use high-precision photometry obtained by the Kepler spacecraft over more than a year to measure oscillations in several hundred red giants. We find many stars whose dipole modes show sequences with approximately regular period spacings. These stars fall into two clear groups, allowing us to distinguish unambiguously between hydrogen-shell-burning stars (period spacing mostly ～ 50 seconds) and those that are also burning helium (period spacing ～ 100 to 300 seconds).     

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

G protein coupled receptors (GPCRs) exhibit a spectrum of functional behaviours in response to natural and synthetic ligands. Recent crystal structures provide insights into inactive states of several GPCRs. Efforts to obtain an agonist-bound active-state GPCR structure have proven difficult due to the inherent instability of this state in the absence of a G protein. We generated a camelid antibody fragment (nanobody) to the human β(2) adrenergic receptor (β(2)AR) that exhibits G protein-like behaviour, and obtained an agonist-bound, active-state crystal structure of the receptor-nanobody complex. Comparison with the inactive β(2)AR structure reveals subtle changes in the binding pocket; however, these small changes are associated with an 11?? outward movement of the cytoplasmic end of transmembrane segment 6, and rearrangements of transmembrane segments 5 and 7 that are remarkably similar to those observed in opsin, an active form of rhodopsin. This structure provides insights into the process of agonist binding and activation.     

Crystal structure of the β2 adrenergic receptor-Gs protein complex

G protein-coupled receptors (GPCRs) are responsible for the majority of cellular responses to hormones and neurotransmitters as well as the senses of sight, olfaction and taste. The paradigm of GPCR signalling is the activation of a heterotrimeric GTP binding protein (G protein) by an agonist-occupied receptor. The β(2) adrenergic receptor (β(2)AR) activation of Gs, the stimulatory G protein for adenylyl cyclase, has long been a model system for GPCR signalling. Here we present the crystal structure of the active state ternary complex composed of agonist-occupied monomeric β(2)AR and nucleotide-free Gs heterotrimer. The principal interactions between the β(2)AR and Gs involve the amino- and carboxy-terminal α-helices of Gs, with conformational changes propagating to the nucleotide-binding pocket. The largest conformational changes in the β(2)AR include a 14 ? outward movement at the cytoplasmic end of transmembrane segment 6 (TM6) and an α-helical extension of the cytoplasmic end of TM5. The most surprising observation is a major displacement of the α-helical domain of Gαs relative to the Ras-like GTPase domain. This crystal structure represents the first high-resolution view of transmembrane signalling by a GPCR.