排序方式: 共有45条查询结果,搜索用时 15 毫秒
1.
2.
First-principle calculation was performed to illustrate the atomic arrangement and segregation behavior of Sn/Ti and O in View the MathML source grain boundary, and the interaction of oxygen interstitials with Sn/Ti atoms on the grain boundary was studied. The analyses on the segregation energies and geometric positions, and the electron densities show that Sn, Ti and O atoms segregate at the Σ3 grain boundary. And the preferred segregation sites of the impurities at View the MathML source were determined. When Sn segregates at grain boundary plane, the O atom prefers to the bulk-like site and shows no segregation tendency at grain boundary, whereas the segregated Ti atom can slightly enhance oxygen segregation at the grain boundary. 相似文献
3.
安全防范工程专业发展方向探讨 总被引:1,自引:1,他引:0
文章介绍了安全防范工程专业发展的历史沿革,根据当今社会生活的变革以及现实公安工作的迫切需求,提出了安全防范工程专业的四个主要发展方向,即安全技术防范工程专业方向、传感与入侵探测技术专业方向、安全检查技术专业方向、安全防范系统工程专业方向。并对安全防范工程专业发展方向的具体实施方法进行了探讨. 相似文献
4.
在满足公路路线实际规范的条件下,公路服务水平的高低、工程的经济性在很大程度上取决于设计阶段的综合线形设计。文章以汽车行驶轨迹为出发点分析平纵线形优化设计的思路,探讨一种更实用的设计方法。 相似文献
5.
6.
7.
Huang Zenghui 《科学之友》2012,(9)
在高层房屋建筑深基坑工程中,基坑支护的设计与施工是一项起关键作用的核心内容,必须给予高度的重视. 相似文献
8.
Adeno-associated virus (AAV) is a promising viral vector and meets most requirements of being a safe biological agent. However, the commercialization of AAV has been hampered due to the limitation of large-scale production, and only a small number of clinical trials have been launched. In recent years, progresses in scalable manufacturing of AAV have dramatically improved AAV- based clinical researches, and have assisted the develop- ment of investigational drug products. An AAVl-based investigational product, Glybera, has been formally approved by European Commission for the treatment of lipoprotein lipase deficiency (LPLD). Glybera was the first gene therapy product in the western world, and the pro- duction process involves a scalable baculovirus-insect cell system. However, many problems still need to be solved to improve the productivity and quality of AAV. The present review gives critical insights into current state-of-the-art scalable producing methodologies of AAV, such as bacu-lovirus-insect cell system, HSV complementation system, and Ad complementation system, along with a discussion on the problems, solutions, and developmental trends.Novel AAV-producing platforms in Saccharomyces cere- visiae and vaccinia virus complementation system will also be discussed. 相似文献
9.
10.
近距离采空区下大断面巷道顶板受煤层开采和巷道掘进两次采掘扰动,为研究两次扰动对巷道顶板稳定性的影响,以任楼煤矿Ⅱ8224切眼巷道为工程背景,利用理论分析、数值模拟及现场实测的方法,对采空区卸荷影响深度和巷道采掘扰动特征进行分析。结果表明:采空区卸荷影响深度的理论计算结果、数值模拟计算结果与钻取岩芯分析结果三者一致,受卸荷影响范围内的岩层会向上隆起;采空区下大断面巷道顶板的下沉时间为14d,最大下沉速度仅为15 mm/d。得出结论:采空区卸荷对煤层底板的扰动破坏影响深度为5.2 m;受采空区卸荷影响,巷道顶板下沉时间、下沉速度和下沉量较小。 相似文献