新时期档案工作浅议

为接受新时期档案工作所面临的机遇与挑战，档案工作必须体现其时代性、把握其规律性、并要富于创造性，实现服务功能的多元化与服务效率的最大化，为两个文明事业的发展提供源源不断的信息资源支持。     

西文期刊回溯建库中几个重要项目的著录

在实践的基础上，从期刊的出版日期、出版周期、卷、期、年、月及其他标识、ISSN、增刊、出版者以及期刊的历史发展等方面对西文期刊机读目录的标准化著录问题进行了探讨。     

关于21世纪图书馆员继续教育问题的思考

论述了21世纪对图书馆员进行继续教育的必要性，介绍了图书馆员继续教育的内容，针对我国图书馆员继续教育的状况，提出了应采取加大投入、进行针对性培训、运用激励机制等措施来加强对图书馆员的继续教育。     

浅谈常见计算机病毒的危害与防治办法

本文对计算机的病毒和危害作了介绍和分析,提出了有关的防治措施和办法.     

廊坊市“文化信息资源共享工程”建设分析与研究

在介绍廊坊市“文化信息资源共享工程”建设现状基础上,阐述了资源共享的意义,分析了资源共享存在的问题,研究了相应的解决方法。     

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases.

Astacin, a digestive zinc-endopeptidase from the crayfish Astacus astacus L., is the prototype for the 'astacin family', which includes mammalian metallo-endopeptidases and developmentally regulated proteins of man, fruitfly, frog and sea urchin. Here we report the X-ray crystal structure of astacin, which reveals a deep active-site cleft, with the zinc at its bottom ligated by three histidines, a water molecule and a more remote tyrosine. The third histidine (His 102) forms part of a consensus sequence, shared not only by the members of the astacin family, but also by otherwise sequentially unrelated proteinases, such as vertebrate collagenases. It may therefore represent the elusive 'third' zinc ligand in these enzymes. The amino terminus of astacin is buried forming an internal salt-bridge with Glu 103, adjacent to His 102. Astacin pro-forms extended at the N terminus, as observed for some 'latent' mammalian astacin homologues, did not exhibit this 'active' conformation, indicating an activation mechanism reminiscent of trypsin-like serine proteinases.     

浅谈新型墙体材料——煤矸石空心砖

煤矸石空心砖是一种新型环保墙体材料，符合国家及山西省出台的限制生产和使用实心黏土砖，鼓励发展新型建筑材料的政策。利用煤矸石制造的空心砖可以作为保温材料，既可节约建筑能耗，又可节约土地资源，减少环境污染。煤矸石空心砖同黏土实心砖相比，具有高强、轻质、隔音、隔热、保温、防震等优点，市场前景良好。     

金属基复合材料界面层阻尼功能研究

采用CVD技术制备了具有不同界面层的C-f/Al金属基复合材料，获得了一种界面层阻尼功能设计的新方法. 研究发现具有特殊界面层的C-f/Al复合材料的抗拉强度、弹性模量和阻尼性能比无界面层时都有明显增加，并且不同界面层的效果不同. 碳层对复合材料阻尼性能的提高效果最大，硅层的提高效果不如碳层，碳硅混合层的效果居中. 涂层的厚度也影响了阻尼提高的效果，较厚的碳层效果更好，这是由于提高了复合材料的阻尼应变振幅效应而产生的. 研究认为发生在界面层的微滑移是其主要的阻尼机制.     

新世纪图书馆员社会角色转换研究综述

就近几年图书馆界关于新世纪馆员意识转换及社会角色转换等方面的研究进行了综述，指出新时期的馆员要实现自我社会角色的转换，首先是要明确转换的必要性，然后采取有效的策略逐步地、系统地推进转换，才能取得较好的效果。     

Fibronectin peptide DRVPHSRNSIT and fibronectin receptor peptide DLYYLMDL arrest gastrulation ofRana pipiens

Gastrulation is characterized by dramatic cell migration which is thought to require the interaction of cell adhesion molecules with extracellular molecules. We have tested two novel peptides, a fibronectin peptide and a fibronectin receptor peptide, for their effects on gastrulation of the leopard frogRana pipiens. The fibronectin peptide DRVPHSRNSIT corresponds to residues 1373–1383 of the cell-binding domain of fibronectin; the receptor peptide DLYYLMDL corresponds to residues 124–131 of 1 subunit of a variety of integrins including 51. Either of these peptides significantly inhibited gastrulation after being microinjected into mid-blastulae. These results indicate that these sequences may correspond to the ligand/receptor interaction sites of fibronectin and its receptor(s).