基于驾驶模拟实验的快速路交织区运行风险评价

对快速路交织区运行风险进行有效评价可为交通组织优化设计与交通管控的实施提供依据.基于8自由度驾驶模拟仿真平台,建立16个场景模拟不同交织区长度、不同交通流密度、不同行驶路径的城市快速路交织区运行状况;基于20名驾驶员的实验数据,分析车辆运行状态特性,并提出快速路交织区运行风险评价指标;进一步分析运行风险评价指标与场景变量的关系,并给出运行风险等级划分标准.研究结果表明:高密度交通流场景下运行风险比低密度交通流场景增大50％;运行风险评价指标与交织区长度呈线性负相关关系,增大交织区长度有利于降低交织区的运行风险.     

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

The mitotic checkpoint protein hsMad2 is required to arrest cells in mitosis when chromosomes are unattached to the mitotic spindle. The presence of a single, lagging chromosome is sufficient to activate the checkpoint, producing a delay at the metaphase-anaphase transition until the last spindle attachment is made. Complete loss of the mitotic checkpoint results in embryonic lethality owing to chromosome mis-segregation in various organisms. Whether partial loss of checkpoint control leads to more subtle rates of chromosome instability compatible with cell viability remains unknown. Here we report that deletion of one MAD2 allele results in a defective mitotic checkpoint in both human cancer cells and murine primary embryonic fibroblasts. Checkpoint-defective cells show premature sister-chromatid separation in the presence of spindle inhibitors and an elevated rate of chromosome mis-segregation events in the absence of these agents. Furthermore, Mad2+/- mice develop lung tumours at high rates after long latencies, implicating defects in the mitotic checkpoint in tumorigenesis.     

汉译《圣经》的语言学价值

《圣经》翻译成汉语经历了很长的历史时期,这期间积累的汉译《圣经》文献资料,是研究汉语的宝贵财富。从现在通行的读本看,现行本《圣经》汉语中包含有浓厚的文言色彩,也有汉语方言成分,其翻译语言还保留了翻译时的中介语特点。对汉译《圣经》的研究,将能够为汉语研究提供宝贵的资料。     

Approach to Enterprise Application Integration with Web Services

IntroductionMostoftheenterprisesmightusesomekindsofisolatedITsystems ,suchasEnterpriseResourcePlanning(ERP )systems,CustomerRelationshipManagement(CRM )systems,SupplyChainManagement (SCM )systems,OfficeAutomation (OA )suitesandsoon ,toautomatedistinctbusinesspractices .Thesesystemsoftencoexistwithawidevarietyofin houseapplications[1] .Inordertoimprovebusinessbyautomatingbusinessprocessesthatspantheseisolatedsystems,theenterpriseneedstointegratetheisolatedsystemsandapplicationswithEnt…