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1.
H. Tsuchiya M. Sato M. Iinuma J. Yokoyama M. Ohyama T. Tanaka I. Takase I. Namikawa 《Cellular and molecular life sciences : CMLS》1994,50(9):846-849
Phytoalexins, defensive compounds produced by plants against microbial infections, were purified fromSophora exigua (Leguminosae) and their growth inhibitory effects on oral cariogenic bacteria were determined in vitro. Among three isolated compounds, 5,7,2,4-tetrahydroxy-8-lavandulylflavanone completely inhibited the growth of oral bacteria including primary cariogenic mutans streptococci, other oral streptococci, actinomycetes, and lactobacilli, at concentrations of 1.56 to 6.25 g/ml. 相似文献
2.
Following the suppression of renewal of rat taste cells by vinblastine sulphate, the preference for sucrose decreased markedly while the aversion to quinine did not change. The results suggest that the sensitivity of taste cells to sucrose decreases with their aging, but the sensitivity to quinine increases. 相似文献
3.
T Sato 《Experientia》1977,33(9):1165-1167
When frog taste cells were stimulated by varying salts after adaptation to water, quinine or acetic acid, a phasic depolarization appeared initially in the receptor potential of taste cells. The initial transient depolarization may be related to the enhancement of an initial phasic response in the taste nerve. 相似文献
4.
Hessa T Meindl-Beinker NM Bernsel A Kim H Sato Y Lerch-Bader M Nilsson I White SH von Heijne G 《Nature》2007,450(7172):1026-1030
5.
A taxonomic review of three Asian species of Hesperonoe (Annelida: Polynoidae) is presented. Hesperonoe hwanghaiensis Uschakov and Wu, 1959 (type locality: Qingdao, China) is redescribed based on five specimens collected from an intertidal site in the Korean coast of the Yellow Sea, as a new record of this species from Korea, which is the only known habitat outside the type locality. Hesperonoe coreensis sp. nov. is described based on nine specimens collected from two intertidal sites in the Korean coast of the Yellow Sea, including the same site as the habitat of H. hwanghaiensis. Hesperonoe japonensis sp. nov. is described by re-examination of many specimens collected from eight intertidal sites and a subtidal one in Japan, which was previously misidentified as H. hwanghaiensis. The three species are clearly distinguishable from one another by the species-specific morphology of the macrotubercles (or marked ridges) on the surface of elytra. All of the three species seemed to be commensal with the burrowing mud shrimp Upogebia major in intertidal flats, except for an additional probable host of another upogebid shrimp Austinogebia narutensis for H. japonensis sp. nov. in a subtidal habitat. The morphological characteristics and host species of the three Asian species are compared with all of the other five congeners known from the North American Pacific and Arctic Sea.http://www.zoobank.org/urn:lsid:zoobank.org:pub:51CB5C5B-0838-48AC-A0BA-8E63AA7628CB 相似文献
6.
Naoki Osada 《Archive for History of Exact Sciences》2013,67(4):457-476
In Of Quadrature by Ordinates (1695), Isaac Newton tried two methods for obtaining the Newton–Cotes formulae. The first method is extrapolation and the second one is the method of undetermined coefficients using the quadrature of monomials. The first method provides $n$ -ordinate Newton–Cotes formulae only for cases in which $n=3,4$ and 5. However this method provides another important formulae if the ratios of errors are corrected. It is proved that the second method is correct and provides the Newton–Cotes formulae. Present significance of each of the methods is given. 相似文献
7.
Onouchi Y Gunji T Burns JC Shimizu C Newburger JW Yashiro M Nakamura Y Yanagawa H Wakui K Fukushima Y Kishi F Hamamoto K Terai M Sato Y Ouchi K Saji T Nariai A Kaburagi Y Yoshikawa T Suzuki K Tanaka T Nagai T Cho H Fujino A Sekine A Nakamichi R Tsunoda T Kawasaki T Nakamura Y Hata A 《Nature genetics》2008,40(1):35-42
Kawasaki disease is a pediatric systemic vasculitis of unknown etiology for which a genetic influence is suspected. We identified a functional SNP (itpkc_3) in the inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) gene on chromosome 19q13.2 that is significantly associated with Kawasaki disease susceptibility and also with an increased risk of coronary artery lesions in both Japanese and US children. Transfection experiments showed that the C allele of itpkc_3 reduces splicing efficiency of the ITPKC mRNA. ITPKC acts as a negative regulator of T-cell activation through the Ca2+/NFAT signaling pathway, and the C allele may contribute to immune hyper-reactivity in Kawasaki disease. This finding provides new insights into the mechanisms of immune activation in Kawasaki disease and emphasizes the importance of activated T cells in the pathogenesis of this vasculitis. 相似文献
8.
H. Miyamoto N. Manabe Y. Akiyama T. Watanabe M. Sugimoto E. Sato 《Cellular and molecular life sciences : CMLS》1994,50(9):808-811
The morphometric parameters of spermatogenic cells in a mouse strain prone to accelerated senescence (SAM-P), a novel murine model of spontaneously promoted aging, were compared with those of a SAM resistant strain (SAM-R) after birth until 40 weeks (mean life span of SAM-P). A mixture of gonocytes and spermatogonia were present in the testis in 1-week-old mice, and no gonocytes were observed in 2-week-old mice. At 6 weeks of age, the absolute number of spermatogonia in SAM-P was 27% greater than that in SAM-R, whereas the cell number in 40-week-old SAM-P was 17% less than in SAM-R. Primary spermatocytes were first observed in 3-week-old animals, and the cell numbers in SAM-P at 3, 5 and 6 weeks were 78%, 31% and 25%, respectively, greater than in SAM-R, whereas the cell number in SAM-P at 40 weeks was 30% less than SAM-R. Round spermatids were first observed in all SAM-P at 4 weeks old, but 20% of SAM-r had no spermatids and the rest had only a few. At 5 and 6 weeks old, the absolute numbers of round spermatids in SAM-P was about 34% and 41%, respectively, greater than in SAM-R, whereas the cell number in 40-week-old SAM-P was about 34% less than SAM-R. These results indicate that testicular maturation begins at an earlier age in SAM-P than SAM-R. Furthermore, at the age of 40 weeks signs of testicular deterioration are evident in SAM-P mice only 相似文献
9.
10.
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta 总被引:18,自引:0,他引:18
Takayanagi H Kim S Matsuo K Suzuki H Suzuki T Sato K Yokochi T Oda H Nakamura K Ida N Wagner EF Taniguchi T 《Nature》2002,416(6882):744-749