D4S—6菌的生物学特性及种的鉴定

Ｄ４Ｓ－６菌根据常规的一些生物学特性，确定其为假单胞菌属；按照假单胞菌属分节检索表的要求，我们最终鉴定Ｄ４Ｓ－６ 菌为泡囊假单胞菌，它能有效地分解虾塘的有机污染物．     

Determination of risperidone in human plasma by HPLC-MS/MS and its application to a pharmacokinetic study in Chinese volunteers

This study presents a rapid, specific and sensitive liquid chromatography/tandem mass spectrometry （LC-MS/MS） assay for determination of risperidone （RIS） in human serum using paroxetine as an internal standard （IS）. An Alltima-C18 column （2.1 mm×100 mm, 3 μm） and a mobile phase consisting of 0.1% formic acid-acetonitrile （40：60, v/v） were used for separation. The analysis was performed by selected reaction monitoring （SRM） method, and the peak area of the m/z 411.3→191.1 transition for RIS was measured versus that of the m/z 330.1→192.1 transition for IS to generate the standard curves. The assay linearity of RIS was confirmed over the range 0.25-50.00 ng/ml and the limit of quantitation was 0.05 ng/ml. The linear range corresponds well with the serum concentrations of the analytes obtained in clinical pharmacokinetic studies. Intraday and interday relative standard deviations were 1.85%-9.09% and 1.56%-4.38%, respectively. The recovery of RIS from serum was in the range of 70.20%-84.50%. The method was successfully applied to investigate the bioequivalence between two kinds of tablets （test versus reference products） in 18 healthy male Chinese volunteers. The result suggests that two formulations are bioequivalent.     

蓖麻花药愈伤组织诱导条件优化

以通蓖5号品种的蓖麻花药为试验材料,研究了不同浓度的蔗糖、不同生长调节剂及pH值对愈伤组织诱导的影响.结果表明,蔗糖在20～40g/L之间均有较高的愈伤诱导率,且随蔗糖浓度的增加而升高;当ZT为3.0mg/L、NAA为1.0mg/L愈伤组织诱导最高;当pH值在6.0时,愈伤组织诱导效果最佳,诱导率达到最高为27.95％,且此时褐化率较低.     

Experimental study on 830 MPa grade pipeline steel containing chromium

The diversity of microstructure and properties of 830 MPa grade pipeline steel containing chromium was investigated by optical microscope and transmission electron microscopy. The main microstructures were multiple configurations, containing lath bainite and granule bainitc. Mechanical properties test results showed that the yield strength and tensile strength improved with increasing chromium content. The toughness and elongation decreased at the same time, so temper process was introduced. Appling proper temper parameters, the values of toughness and elongation were improved dramatically, and the strength decreased slightly.     

Inter-phase selective corrosion of γ -TiAl alloy in molten salt environment at high temperature

Hot corrosion behavior of Ti-48Al-2Cr-2Nb alloy in molten salt environment of 75% Na2SO4 and 25% NaCl (mass fraction) at 800 °C was studied using oxida tion kinetics analysis, scanning electron microscopy, X-ray energy dispersive and X- ray diffraction analyses. The inter-phase selective corrosion, which caused the corrosion pits initiated from lamellar interfaces and the preferential corrosion of α2 phases, was observed during the hot corrosion of the alloy. The common controls of thermodynamic and kinetics in corrosion reactions with fluxing and active oxidation process were considered the essential hot corrosion mechanisms of the alloy. Moreover, lamellar refinement was proved to be an effective way to mitigate the inter-phase selective corrosion of the alloy in molten salts.     

基于单位质量刚度的白车身轻量化研究

在白车身早期设计中,可通过优化各零部件的厚度和形状,达到汽车轻量化的目的．作为白车身重要的性能指标,弯曲刚度、扭转刚度、一阶弯曲模态、一阶扭转模态通常作为早期设计的优化目标,然而这些性能不能量化变量对轻量化的影响,通过将这些性能指标与质量有机结合,提出了可以综合考虑车身各项性能的单位质量刚度（白车身单位质量上的刚度）概念,以用于量化白车身轻量化的程度．将这些单位质量刚度作为目标值,进行灵敏度分析,通过量化各变量对轻量化的影响,选出有利于轻量化的变量,并基于NSGA—II算法,对白车身轻量化进行多目标优化．     

阴道加特纳菌抗体检测的临床应用

目的　采用酶标葡萄球菌A蛋白(HRP SPA)检测细菌性阴道病患者血清中阴道加特纳菌抗体,并与细菌培养相比较.方法　HRP SPA测定法.结果　70例临床标本阴道加特纳菌抗体阳性检出率为65.7%;细菌培养检出阴道加特纳菌阳性检出率为30.0%;两种方法比较P<0.01.结论　本方法具有简便、快速和不需要特殊仪器等优点.     

An ε-domination based two-archive 2 algorithm for many-objective optimization

The two-archive 2 algorithm(Two_Arch2) is a manyobjective evolutionary algorithm for balancing the convergence,diversity,and complexity using diversity archive(DA) and convergence archive(CA).However,the individuals in DA are selected based on the traditional Pareto dominance which decreases the selection pressure in the high-dimensional problems.The traditional algorithm even cannot converge due to the weak selection pressure.Meanwhile,Two_Arch2 adopts DA as the output of the algorithm which is hard to maintain diversity and coverage of the final solutions synchronously and increase the complexity of the algorithm.To increase the evolutionary pressure of the algorithm and improve distribution and convergence of the final solutions,an ε-domination based Two_Arch2 algorithm(ε-Two_Arch2) for many-objective problems(MaOPs) is proposed in this paper.In ε-Two_Arch2,to decrease the computational complexity and speed up the convergence,a novel evolutionary framework with a fast update strategy is proposed;to increase the selection pressure,ε-domination is assigned to update the individuals in DA;to guarantee the uniform distribution of the solution,a boundary protection strategy based on I_ε+ indicator is designated as two steps selection strategies to update individuals in CA.To evaluate the performance of the proposed algorithm,a series of benchmark functions with different numbers of objectives is solved.The results demonstrate that the proposed method is competitive with the state-of-the-art multi-objective evolutionary algorithms and the efficiency of the algorithm is significantly improved compared with Two_Arch2.     

狂欢化：韩寒《光荣日》的后现代叙事特征

“狂欢化”是巴赫金在研究欧洲中世纪和文艺复兴时期民间文化及文学创作的基础上提出并系统阐释的一种文化与文学理论。在中周小说界经历多种“现代性”探索与实验后却仍然迷茫于“不知路在何方”之时,狂欢化理论为小说创作指点了“后现代”之路。韩寒的《光荣日》是具有鲜明的后现代狂欢化叙事特征的小说,主要表现为空间戏仿化、人物边缘化、情节双声化和语言粗鄙化。     

一个五变量钙振荡模型中的分支分析

主要从分支的角度分析了一个五变量的胞内钙振荡模型中的钙振荡现象,首次从理论上证明了细胞质内和内质网上的钙离子浓度周期性振荡现象可通过系统平衡点发生Hopf分支而产生。此外,通过数值模拟,我们还发现了此模型的钙振荡现象不是单一形式的,存在着拟周期、混沌等复杂形式的振荡。