排序方式: 共有47条查询结果,搜索用时 15 毫秒
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提出TCP/IP在过程控制中的应用. 评价TCP/IP控制系统性能,通过传统控制系统与TCP/IP控制系统的比较,指出采用TCP/IP 控制系统的优缺点. 说明过程控制技术中,采用TCP/IP是一种更好的选择. 相似文献
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Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells 总被引:1,自引:0,他引:1
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Jiraporn Ousingsawat Inês Cabrita Podchanart Wanitchakool Lalida Sirianant Stefan Krautwald Andreas Linkermann Rainer Schreiber Karl Kunzelmann 《Cellular and molecular life sciences : CMLS》2017,74(1):173-181
Activated receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain like (MLKL) are essential components of the necroptotic pathway. Phosphorylated MLKL (pMLKL) is thought to induce membrane leakage, leading to cell swelling and disintegration of the cell membrane. However, the molecular identity of the necroptotic membrane pore remains unclear, and the role of pMLKL for membrane permeabilization is currently disputed. We observed earlier that the phospholipid scramblase and ion channel TMEM16F/anoctamin 6 cause large membrane currents, cell swelling, and cell death when activated by a strong increase in intracellular Ca2+. We, therefore, asked whether TMEM16F is also central to necroptotic cell death and other cellular events during necroptosis. Necroptosis was induced by TNFα, smac mimetic, and Z-VAD (TSZ) in NIH3T3 fibroblasts and the four additional cell lines HT29, 16HBE, H441, and L929. Time-dependent changes in intracellular Ca2+, cell morphology, and membrane currents were recorded. TSZ induced a small and only transient oscillatory rise in intracellular Ca2+, which was paralleled by the activation of outwardly rectifying Cl? currents, which were typical for TMEM16F/ANO6. Ca2+ oscillations were due to Ca2+ release from endoplasmic reticulum, and were independent of extracellular Ca2+. The initial TSZ-induced cell swelling was followed by cell shrinkage. Using typical channel blockers and siRNA-knockdown, the Cl? currents were shown to be due to the activation of ANO6. However, the knockdown of ANO6 or inhibitors of ANO6 did not inhibit necroptotic cell death. The present data demonstrate the activation of ANO6 during necroptosis, which, however, is not essential for cell death. 相似文献
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A number of IDSs have been proposed for a networked or distributed environment. A modified D-IDS using federated peer-to-peer architecture, MCR (Multicast Reflector) and modified shaker protocol were proposed. The suggested scheme can be implemented easily and performs the information sharing between low-level IDS agents. As all users within a group monitor each other's, the common control server can perform detect intrusions with less cost and support the detection of the inside intruders. 相似文献
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木屑新法制草酸的研究 总被引:3,自引:0,他引:3
本文简要地介绍了木屑新法制草酸的原理、工艺流程和操作方法.制得的草酸经分析质量符合二级品标准.利用木屑生产草酸方法简单,有一定经济效益、环境效益和社会效益 相似文献
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介绍了一种采用超声波血浓密度计测量家兔血容量的新方法。通过测定家兔循环血液中注射生理盐水后其血液密度和血浆密度的变化来确定血容量,与传统的血容量测量方法相比,密度法具有结构简单,测量精度高,对动物无害等优点。 相似文献
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作者在前人工作的基础上,分离了大豆根瘤中感染细胞的原生质体,分离得到的感染细胞原生质体产量较高。经显微观察和几种细胞化学方法检测的结果表明,原生质体纯度高、破损少、具很强的生活力。对于以其为材料的生化研究具有一定的实际应用价值。 相似文献