集成电路设计产业产品创新趋势研究——国际片上系统（SOC）IP核发展现状及对策分析

基于国际集成电路设计产业的分析，系统阐述了国际SOCIP核的发展状况，指出SOC设计将是集成电路设计企业技术创新的发展方向。提出了一些国际SOCIP核发展的对策，包括口核标准化、SOC技术平台开发及加强与Foundry的合作。     

星星草种群地上生物量形成规律的数学拟合

在松嫩盐碱草地上，我们对人工种植在碱斑土壤上生长一年、二年、三年、六星星草坪以及野生的天然星星草地中的星星草种群地上生物量的季节动态进行了测定，并进行数学拟合。用Ｌｏｇｉｓｔｉｃ曲线拟合时，抽穗期以前拟合情况较好，但不能很好地拟合星星草种群大生物量后衰老的过程。用一元多次曲线则能很好地拟合星星草种群地上生物量随生育时间的季节动态。     

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases.

Astacin, a digestive zinc-endopeptidase from the crayfish Astacus astacus L., is the prototype for the 'astacin family', which includes mammalian metallo-endopeptidases and developmentally regulated proteins of man, fruitfly, frog and sea urchin. Here we report the X-ray crystal structure of astacin, which reveals a deep active-site cleft, with the zinc at its bottom ligated by three histidines, a water molecule and a more remote tyrosine. The third histidine (His 102) forms part of a consensus sequence, shared not only by the members of the astacin family, but also by otherwise sequentially unrelated proteinases, such as vertebrate collagenases. It may therefore represent the elusive 'third' zinc ligand in these enzymes. The amino terminus of astacin is buried forming an internal salt-bridge with Glu 103, adjacent to His 102. Astacin pro-forms extended at the N terminus, as observed for some 'latent' mammalian astacin homologues, did not exhibit this 'active' conformation, indicating an activation mechanism reminiscent of trypsin-like serine proteinases.     

大尺寸YBa2Cu3O7—δ超导体的研制

利用固相反应法成功地制备了直径为100mm,厚为5mm的大尺寸YBa_2Cu_3O_(7-δ)超导体。在通氧,930℃热处理45min后,超导体的上限转变温度为94K,零电阻温度为92K。x射线衍射进行物相定性,扫描电镜进行形貌和超导电性关系的对比观察。选区电子衍射给出YBa_2Cu_3O_(7-δ)超导体的晶格参数为a=0.348nm,b=0.377nm,c=0.716nm,属于正交晶系。     

一类泛圈图

本文证明了如果G是2连通无爪图,G不是圈,n=|v(G)|>q,G的每个导出子图A都满足φ(a_1,a_2),且G中不存在W′作为其导出子图,则G是泛圈图。     

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease.

Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional growth factor that has profound regulatory effects on many developmental and physiological processes. Disruption of the TGF-beta 1 gene by homologous recombination in murine embryonic stem cells enables mice to be generated that carry the disrupted allele. Animals homozygous for the mutated TGF-beta 1 allele show no gross developmental abnormalities, but about 20 days after birth they succumb to a wasting syndrome accompanied by a multifocal, mixed inflammatory cell response and tissue necrosis, leading to organ failure and death. TGF-beta 1-deficient mice may be valuable models for human immune and inflammatory disorders, including autoimmune diseases, transplant rejection and graft versus host reactions.     

结合环的一个结构定理

本文讨论了一般结合环与(左)S-单式周期环在一定条件下的结构问题,得出它们分别是局部交换环与诣零交换环,或为局部交换环的亚直和。同时,推广和改进了文献[l]的结果。     

Intramammary expression and therapeutic effect of a human lysozyme-expressing vector for treating bovine mastitis

To develop a gene therapy strategy for treating bovine mastitis, a new mammary-specific vector containing human lysozyme (hLYZ) cDNA and kanamycin resistance gene was constructed for intramammary expression and clinical studies. After one time acupuncture or intracisternal infusion of healthy cows with 400 μg of the p215C3LYZ vector, over 2.0 μg/ml of rhLYZ could be detected by enzymatic assay for about 3 weeks in the milk samples. Western blotting showed that rhLYZ secreted into milk samples from the vector-injected cows had molecular weight similar to that of the natural hLYZ in human colostrums. Twenty days after the primary injection, the quarters were re-injected with the same vector by quarter acupuncture and even higher concentrations of rhLYZ could be detected. Indirect competitive ELISA of milk samples showed that the vector injection did not induce detectable humoral immune response against hLYZ. Clinical studies showed that twice acupuncture of quarters with the p215C3LYZ vector had overt therapeutic effect on clinical and subclinical mastitis previously treated with antibiotics, including disappearance of clinical symptoms and relatively high microbiological cure rates. These data provide a solid rationale for using the vector to develop gene therapy for treating bovine mastitis.     

超高灵敏显色反应测定痕量锑──锑（Ⅲ）─罗丹明B─碘化钾体系

本文研究结果表明，水溶性大分子化合物阿拉伯胶和非离子表面活性剂ＴｒｉｔｏｎＸ－１００共同存在下，锑碘配阴离子和罗丹明Ｂ的显色反应具有很高的灵敏度。缔合物的最大吸收在５ｇ０ｎｍ，摩尔吸光系数ε＝６．１×１０￣５Ｌ·ｍｏｌ－１·ｃｍ－１。用巯基棉富集锑，分离干扰离子。本法可应用于有色金属中痕量锑的测定。     

GDX—硅胶混合薄层色谱板的效率和定量性能

对用ＧＤＸ－１０２－硅胶Ｇ、有机粘合剂研制出的混合薄层板进行性能测试，评价了其在硝基苯胺异构体、酸性食品染料分离测试方面的应用，得到好的结果。