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IntroductionGenetic manipulation of bacteria has become apowerful tool for elucidating fundamentalbiological mechanisms.While many techniques areavailable to introduce foreign DNA into severalbacterial species[1 ] ,some bacteria,such asStreptococcus spp.,have proven to be resistant totransformation with mostprotocols thathave beendescribed.In addition,there are large differencesin the transform ability among various strains ofStreptococcusspp. Streptococci have been divided into six majorph… 相似文献
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