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1.
郭福奎 《山东科技大学学报(自然科学版)》1996,(4)
设θ1与θ2组成一个Hamilton对,且设θ2可逆。记Φ=θ1θ1-1。本文证明了:Φiθ2是一类Hamilton算子,其中ci(i=0,1,2,3)是任意常数。 相似文献
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C. Kitada M. Fujino Y. Kamiya A. Sakurai S. Tamura N. Takahashi E. Tsuchiya K. Abe S. Fukui 《Cellular and molecular life sciences : CMLS》1979,35(10):1275-1276
Summary The inducing factor of mating tube formation ofRhodosporidium turuloides, named rhodotorucine A (H-Tyr-Pro-Glu-Ile-Ser-Trp-Thr-Arg-Asn-Gly-Cys(S-farnesyl)-OH), has been synthesized to confirm the structure proposed for the natural lipopeptide. The synthetic S-farnesyl undecapeptide has identical Rf values on TLC using several different solvents, and also the same biological activity as the natural hormone.Acknowledgments. We wish to express our thanks to Drs E. Ohmura, M. Nishikawa and M. Yoneda of Takeda Chemical Industries and Dr I. Banno of Institute for Fermentation, Osaka, for their encouragement throughout this work. 相似文献
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Zusammenfassung Die Synthese von 5,7,4-Trihydroxy-3,8,3-trimethoxyflavon aus 2,4,6-Trihydroxy-3,-dimethoxyacetophenon wird beschrieben. Das synthetische Präparat ist mit einem ausCyanostegia angustifolia Turcz. isolierten Pigment identisch. 相似文献
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SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling 总被引:9,自引:0,他引:9
Shinohara M Terada Y Iwamatsu A Shinohara A Mochizuki N Higuchi M Gotoh Y Ihara S Nagata S Itoh H Fukui Y Jessberger R 《Nature》2002,416(6882):759-763
Phosphoinositide-3-OH kinase (PI(3)K), activated through growth factor stimulation, generates a lipid second messenger, phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3). PtdIns(3,4,5)P3 is instrumental in signalling pathways that trigger cell activation, cytoskeletal rearrangement, survival and other reactions. However, some targets of PtdIns(3,4,5)P3 are yet to be discovered. We demonstrate that SWAP-70, a unique signalling protein, specifically binds PtdIns(3,4,5)P3. On stimulation by growth factors, cytoplasmic SWAP-70, which is dependent on PI(3)K but independent of Ras, moved to cell membrane rearrangements known as ruffles. However, mutant SWAP-70 lacking the ability to bind PtdIns(3,4,5)P3 blocked membrane ruffling induced by epidermal growth factor or platelet-derived growth factor. SWAP-70 shows low homology with Rac-guanine nucleotide exchange factors (GEFs), and catalyses PtdIns(3,4,5)P3-dependent guanine nucleotide exchange to Rac. SWAP-70-deficient fibroblasts showed impaired membrane ruffling after stimulation with epidermal growth factor, and failed to activate Rac fully. We conclude that SWAP-70 is a new type of Rac-GEF which, independently of Ras, transduces signals from tyrosine kinase receptors to Rac. 相似文献
7.
Reversible cyclic AMP-dependent change in distribution of myosin thick filaments in Dictyostelium 总被引:2,自引:0,他引:2
Myosin is thought to act as a major mechanochemical transducer in non-muscle cell motility, but the in situ organization of the molecules has not yet been determined. Here we report the localization of myosin 'rods', analogous to the thick filaments of muscle, by ameliorated immunofluorescence and demonstrate the dynamic translocation of these rods in response to exogenously added cyclic AMP, which is a chemoattractant for Dictyostelium amoebae. On addition of cyclic AMP, we observed instantaneous shedding of the endoplasmic myosin followed by an increase in cortical rods, the original distribution being recovered in a few minutes. We conclude that myosin filaments mediate Dictyostelium cell movement, probably by an assembly/disassembly cycle of the molecules in response to a chemotactic stimulus. 相似文献
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郭福奎 《山东科技大学学报(自然科学版)》1991,(1)
本文给出了Boussinesq方程的含两个任意参数的双线性的Backlund变换,推广了已知结果 相似文献
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Zusammenfassung Axillarin (5, 7, 3, 4-Tetrahydroxy-3,6-dimethoxyflavon). 5,3,4-Trihydroxy-3,6,7-trimethoxyflavon und 5,7,3,4-Tetrahydroxy-3,8-dimethoxyflavon wurden synthetisiert. 相似文献