响应面法优化地榆根多酚提取工艺

以吉林地区地榆根为原料,采用响应面法优化超声波辅助提取地榆根多酚的工艺条件.在原料粒度、超声功率、超声时间、液料比、乙醇体积分数单因素试验的基础上,进行Box-Behnken设计,优选出超声波提取地榆根多酚的最佳工艺条件:原料粒度380~250μm、超声功率324.8 W、超声时间19.65 min、液料比[V(液)∶m(料)]15.75∶1、乙醇体积分数51.5%,多酚提取率为6.546%,与预测值吻合,由此表明此响应面模型对地榆根多酚提取具有良好的预测作用.     

地方城市空间要素规划建设时序研究:以清代台湾省为例*

古代地方城市空间要素的规划建设时序是城市史、 规划史研究的重要问题。本文以清代台湾省 16 座府、州、 县、厅城市为例,选取治署、城垣、学宫、三坛一庙四类空间要素为指标,研究其规划建设时序的特征与规律。先分别论述四类要素在诸城规划建设过程中的时序特征,再分析四类要素之间的时序规律,解读其成因与意义。     

Identification of noncoding RNA-encoded proteins on lipid droplets

With the rapid development of high-throughput sequencing technologies, it has recently become evident that the eukaryotic genome is extensively transcribed [1,2...     

非保守市场的建模原则

在非保守型市场的情形下，推广了「１」的市场建模原则。     

6-溴异香兰素诱发人宫颈癌上皮细胞纺锤体损伤及有丝分裂灾变死亡

 研究香兰素衍生物中的6-溴异香兰素（6-溴-5-羟基-4-甲氧基苯甲醛,BVAN08）对人宫颈癌上皮（HeLa）细胞纺锤体结构、有丝分裂的影响,及杀死癌细胞的相关机制,为开发新的抗癌药物提供理论依据。研究发现BVAN08对体外培养的人HeLa细胞具有剂量依赖性致死效应。通过抗?琢-微管蛋白抗体和抗?茁-微管蛋白抗体免疫荧光标记和激光共聚焦显微镜观察发现其机制是：BVAN08对细胞纺锤体结构造成破坏,诱发产生大量的多中心体细胞,使细胞阻滞在有丝分裂期。异常多极纺锤体细胞的百分率与BVAN08呈浓度依赖效应关系。荧光染料Hoechst33258染色观察到多微核或细胞核割裂和染色质凝集现象,也证实BVAN08诱发Hela细胞有丝分裂灾变死亡。同时免疫印迹实验还发现,BVAN08可导致细胞周期转录调节因子FoxM1（Forkhead box）及其下游靶分子CyclinB1的降解,参与有丝分裂的FoxM1蛋白失活,这表明BVAN08通过抑制FoxM1蛋白的表达是导致细胞纺锤体装配异常、细胞发生有丝分裂灾变死亡的分子机制之一。研究结果提示BVAN08诱发Hela细胞新的死亡方式,具有被开发为新型抗癌药物的潜力。     

Calculation of non－mono chromatic reflectance of Co／Sb multilayer

It is well known that the structure defects, such as the interfacial roughness, interdiffusion and chemical reaction at interface, can degrade the optical properties for soft X-ray multilayer[1—5]. For example, the interfacial rough-ness can lead to a loss of spectral reflectance, which has been investigated for many years, and number theories for the scattering of electromagnetic radiation by interfacial roughness have been formulated[6,7]. In addition, the fluc-tuation of the period can als…     

Efficiency of Cache Mechanism for Network Processors

With the explosion of network bandwidth and the ever-changing requirements for diverse network-based applications, the traditional processing architectures, i.e., general purpose processor (GPP) and application specific integrated circuits (ASIC) cannot provide sufficient flexibility and high performance at the same time. Thus, the network processor (NP) has emerged as an alternative to meet these dual demands for today's network processing. The NP combines embedded multi-threaded cores with a rich memory hierarchy that can adapt to different networking circumstances when customized by the application developers. In today's NP architectures, multithreading prevails over cache mechanism, which has achieved great success in GPP to hide memory access latencies. This paper focuses on the efficiency of the cache mechanism in an NP. Theoretical timing models of packet processing are established for evaluating cache efficiency and experiments are performed based on real-life network backbone traces. Testing results show that an improvement of nearly 70% can be gained in throughput with assistance from the cache mechanism. Accordingly, the cache mechanism is still efficient and irreplaceable in network processing, despite the existing of multithreading.     

浓可可悬浮体的流变特性

采用Ｂｒａｂｅｎｄｅｒ Ｒｈｅｏｔｒｏｎ流变仪及带槽测量系统，测量了不同体积分数的浓哥可悬浮体（Ⅰ）在６０℃下的流变特性。实验发现，Ⅰ呈明显的非牛顿性，剪应力与剪切率从ＨＨｅｒｓｃｈｅｌ－Ｂｕｌｋｅｙ方程。Ⅰ的屈服应力采用外推法及多叶片法测量求出，并使用适当的模型以表示同不体积分数下悬浮体的屈服应力，此计算值在合理范围与测量值相符。对高浓度Ⅰ的弹性贮能模量的测量表明，物系具有弹性。物系触变性则用流     

非牛顿流体的微观混合

采用改进的化学偶合法，研究了半连续搅拦槽内粘稠介质的微观混合规律，分析了物系粘度、搅拦转速、加料速度及其体积比，浆型及其组合对微观混鸽 有征参数－分隔指数的影响。结果表明，粘度增加使微观混合变差，但是分隔指数的变化幅度因粘度范围而异；提高搅拦转速对于改善微观混合的作用有限，尤其假塑性充体的这一相应的限定转速更低；雷诺数不能作为放大准则；兼顾剪切循环作用的组合浆具有改进非牛顿粘稠介质微观混合的显著效