树在风中摆动的计算机实时模拟方法研究

提出了一种生成树叶和树枝在风中摆动动画的计算机方法,该方法考虑了风速、风力和噪音.根据空气动力学给出了一个能很好反映风的物理作用的计算公式,并在力学分析的基础上给出了计算树叶和树枝变形的数学公式,利用这些公式,并结合1/fβ噪音技术,可以计算每一个树叶和树枝的变形,进而可以得到整个树的变形.利用这种方法可以很快得到树在风中摆动的效果,实现树在风中摆动的计算机模拟.     

A genome-wide association study identifies three new risk loci for Kawasaki disease

We performed a genome-wide association study (GWAS) of Kawasaki disease in Japanese subjects using data from 428 individuals with Kawasaki disease (cases) and 3,379 controls genotyped at 473,803 SNPs. We validated the association results in two independent replication panels totaling 754 cases and 947 controls. We observed significant associations in the FAM167A-BLK region at 8p22-23 (rs2254546, P = 8.2 × 10(-21)), in the human leukocyte antigen (HLA) region at 6p21.3 (rs2857151, P = 4.6 × 10(-11)) and in the CD40 region at 20q13 (rs4813003, P = 4.8 × 10(-8)). We also replicated the association of a functional SNP of FCGR2A (rs1801274, P = 1.6 × 10(-6)) identified in a recently reported GWAS of Kawasaki disease. Our findings provide new insights into the pathogenesis and pathophysiology of Kawasaki disease.