链条炉存在的问题及解决方法

从炉排横向配风不均、风室压火、煤层厚度阻力及锅炉燃烧等方面分析了链条锅炉存在的问题，并针对存在的问题提出了相应的解决办法。     

芦岭矿采空区煤炭自燃发火与开采技术关系的试验研究

采用了包括多点热电偶测定采空区遗煤温度、应用六氟化硫气体示踪和测定漏风压差等综合技术手段研究分析了漏风分布规律。结果发现,遗煤温度变化受漏风温度和漏风强度影响较大;停采线漏风的量及漏风时间受主要进、回风道的布置以及采掘接替安排的影响。由于采用无煤柱开采技术,三个相邻阶段的采空区之间连通,存在漏风,最后又从开采技术上提出了防火措施。     

巧用Visual FoxPro制作套表打印

从报表创建、报表布局及打印调试等方面介绍了利用Visual FoxPro的快速报表实现套表打印的具体操作步骤。在Visual FoxPro下制作报表简单、实用、方便，很好地解决了数据套表打印问题。     

浅孔密集钻注浆及有关参数的确定

本文阐述采用浅孔密集钻注浆时,钻孔的布置和设计,注浆材料的粒度分级和水土比的简易测定方法,以及泥浆输送中计算水力坡度、临界流速和倍线时有关参数的确定。     

Structure and gating mechanism of the acetylcholine receptor pore

The nicotinic acetylcholine receptor controls electrical signalling between nerve and muscle cells by opening and closing a gated, membrane-spanning pore. Here we present an atomic model of the closed pore, obtained by electron microscopy of crystalline postsynaptic membranes. The pore is shaped by an inner ring of 5 alpha-helices, which curve radially to create a tapering path for the ions, and an outer ring of 15 alpha-helices, which coil around each other and shield the inner ring from the lipids. The gate is a constricting hydrophobic girdle at the middle of the lipid bilayer, formed by weak interactions between neighbouring inner helices. When acetylcholine enters the ligand-binding domain, it triggers rotations of the protein chains on opposite sides of the entrance to the pore. These rotations are communicated through the inner helices, and open the pore by breaking the girdle apart.     

浅谈物理习题条件的隐蔽性

就高中物理高考命题中常见的条件隐蔽性问题进行了讨论，得出高中物理高考命题方式虽然很多，但只要学生概念清楚、判断准确，即能解题。分别以几种不同命题方式对其条件的隐蔽性进行了详尽的分析，对提高学生判断、推理、分析等综合能力具有一定的帮助。     

程潮铁矿体视化仿真系统地质数据库的建立

通过分析程潮铁矿地质采样数据的特点，结合矿床及其开采设计体视化仿真系统的性能需求，从数据库表结构，表间关系及数据的录入处理等三个方面，描述了矿床地质数据库建立过程，采用ADO相关技术实现了地质数据库管理子系统，实践表明，本系统是合理的、有效的。     

搅拌磨超细粉磨金精矿工艺的优化

研究了搅拌磨超细粉磨金精矿的工艺,考察了主要参数对粉磨效果的影响.结果表明,通过优化磨矿过程中各种影响因素,可以获得细度-20μm＞99%的金精矿产品.     

Lipid-protein interactions in double-layered two-dimensional AQP0 crystals

Lens-specific aquaporin-0 (AQP0) functions as a specific water pore and forms the thin junctions between fibre cells. Here we describe a 1.9 A resolution structure of junctional AQP0, determined by electron crystallography of double-layered two-dimensional crystals. Comparison of junctional and non-junctional AQP0 structures shows that junction formation depends on a conformational switch in an extracellular loop, which may result from cleavage of the cytoplasmic amino and carboxy termini. In the centre of the water pathway, the closed pore in junctional AQP0 retains only three water molecules, which are too widely spaced to form hydrogen bonds with each other. Packing interactions between AQP0 tetramers in the crystalline array are mediated by lipid molecules, which assume preferred conformations. We were therefore able to build an atomic model for the lipid bilayer surrounding the AQP0 tetramers, and we describe lipid-protein interactions.     

Shugoshin collaborates with protein phosphatase 2A to protect cohesin

Sister chromatid cohesion, mediated by a complex called cohesin, is crucial--particularly at centromeres--for proper chromosome segregation in mitosis and meiosis. In animal mitotic cells, phosphorylation of cohesin promotes its dissociation from chromosomes, but centromeric cohesin is protected by shugoshin until kinetochores are properly captured by the spindle microtubules. However, the mechanism of shugoshin-dependent protection of cohesin is unknown. Here we find a specific subtype of serine/threonine protein phosphatase 2A (PP2A) associating with human shugoshin. PP2A colocalizes with shugoshin at centromeres and is required for centromeric protection. Purified shugoshin complex has an ability to reverse the phosphorylation of cohesin in vitro, suggesting that dephosphorylation of cohesin is the mechanism of protection at centromeres. Meiotic shugoshin of fission yeast also associates with PP2A, with both proteins collaboratively protecting Rec8-containing cohesin at centromeres. Thus, we have revealed a conserved mechanism of centromeric protection of eukaryotic chromosomes in mitosis and meiosis.