手性药物拆分方法的研究

本通过对几种拆分手性药物的方法的列举，比较几种方法，详细介绍了几种方法的特点，以及它们的不同作用。各个方法中又列出了不同的线索，根据这些线索来研究这几种拆分的方法，它们的优缺点以及针对这些缺点的解决方法，最后给出了几个典型的用该方法的实验，以辨别它们的效用。     

An influence of solar spectral variations on radiative forcing of climate

The thermal structure and composition of the atmosphere is determined fundamentally by the incoming solar irradiance. Radiation at ultraviolet wavelengths dissociates atmospheric molecules, initiating chains of chemical reactions-specifically those producing stratospheric ozone-and providing the major source of heating for the middle atmosphere, while radiation at visible and near-infrared wavelengths mainly reaches and warms the lower atmosphere and the Earth's surface. Thus the spectral composition of solar radiation is crucial in determining atmospheric structure, as well as surface temperature, and it follows that the response of the atmosphere to variations in solar irradiance depends on the spectrum. Daily measurements of the solar spectrum between 0.2?μm and 2.4?μm, made by the Spectral Irradiance Monitor (SIM) instrument on the Solar Radiation and Climate Experiment (SORCE) satellite since April 2004, have revealed that over this declining phase of the solar cycle there was a four to six times larger decline in ultraviolet than would have been predicted on the basis of our previous understanding. This reduction was partially compensated in the total solar output by an increase in radiation at visible wavelengths. Here we show that these spectral changes appear to have led to a significant decline from 2004 to 2007 in stratospheric ozone below an altitude of 45?km, with an increase above this altitude. Our results, simulated with a radiative-photochemical model, are consistent with contemporaneous measurements of ozone from the Aura-MLS satellite, although the short time period makes precise attribution to solar effects difficult. We also show, using the SIM data, that solar radiative forcing of surface climate is out of phase with solar activity. Currently there is insufficient observational evidence to validate the spectral variations observed by SIM, or to fully characterize other solar cycles, but our findings raise the possibility that the effects of solar variability on temperature throughout the atmosphere may be contrary to current expectations.     

普通化学实验教学改革探索与实践

针对多年来农业院校传统的普通化学实验课教学,进行了教学模式、教学内容、考核方式和实验管理体系等全方位的改革探索和实践.结果表明,经过实验教学改革与实践使学生的实验基本技能、综合素质能力和实验水平有了很大的提高,取得了满意的教学效果.