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排序方式: 共有98条查询结果,搜索用时 629 毫秒
1.
本文根据使用新技术──双回路注(放)水系统在63上10工作面综采放顶煤开采覆岩破坏的探测结果,结合其它采矿方法的实测结果,应用断裂力学理论,研究了放顶煤开采覆岩移动变形破坏特征,为矿井安全生产提供了依据。  相似文献   
2.
A second generation human haplotype map of over 3.1 million SNPs   总被引:2,自引:0,他引:2  
We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25-35% of common SNP variation in the populations surveyed. The map is estimated to capture untyped common variation with an average maximum r2 of between 0.9 and 0.96 depending on population. We demonstrate that the current generation of commercial genome-wide genotyping products captures common Phase II SNPs with an average maximum r2 of up to 0.8 in African and up to 0.95 in non-African populations, and that potential gains in power in association studies can be obtained through imputation. These data also reveal novel aspects of the structure of linkage disequilibrium. We show that 10-30% of pairs of individuals within a population share at least one region of extended genetic identity arising from recent ancestry and that up to 1% of all common variants are untaggable, primarily because they lie within recombination hotspots. We show that recombination rates vary systematically around genes and between genes of different function. Finally, we demonstrate increased differentiation at non-synonymous, compared to synonymous, SNPs, resulting from systematic differences in the strength or efficacy of natural selection between populations.  相似文献   
3.
With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and we also developed new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population. The analysis reveals more than 300 strong candidate regions. Focusing on the strongest 22 regions, we develop a heuristic for scrutinizing these regions to identify candidate targets of selection. In a complementary analysis, we identify 26 non-synonymous, coding, single nucleotide polymorphisms showing regional evidence of positive selection. Examination of these candidates highlights three cases in which two genes in a common biological process have apparently undergone positive selection in the same population:LARGE and DMD, both related to infection by the Lassa virus, in West Africa;SLC24A5 and SLC45A2, both involved in skin pigmentation, in Europe; and EDAR and EDA2R, both involved in development of hair follicles, in Asia.  相似文献   
4.
针对分布式建立与存储的领域本体主题图在融合过程中的语义与结构重复问题以及冗余信息的判断与消除问题,提出了基于语义词典与语料库相结合的主题图融合算法(TMMC),给出了概念相似度计算以及同义关系、整体部分关系等的处理方法.对本体中概念进行基于HowNet语义词典及其他语义词典的多层次相似度计算,定义概念间不同语义关系的融合规则,针对专业领域本体中大量术语词典未收录的问题,提出基于语料库的概念相似度算法,并对计算机教育专业领域扩展主题图进行了融合实验.实验结果表明,TMMC提高了融合的准确率与查全率.  相似文献   
5.
针对采用有限差分法实施凝固过程数值模拟时数据结构的特点,提出了采用背面消除和画家方法进行消隐以生成三维图形的方法.为了提高绘图的速度,提出了替代视向变换矩阵运算的一种简便算法.根据由数值计算得到的铸件凝固时间,提出了在二维剖面上显示凝固动态过程的方法.经过实践证明,提出的方法可以快速地完成上千万网格单元数据的后处理.  相似文献   
6.
A finite-difference method with spatially non-uniform grids was developed to simulate elastic wave propagation in heterogeneous anisotropic media. The method is very simple and requires less compution time. Complicated geometric structures, such as low-velocity layers, cased boreholes and nonplanar interfaces, are treated with fine non-uniform grids. Unlike the multi-grid scheme, this method does not require interpolation between the fine and coarse grids and all grids are Computed in the same spatial iteration. Planar or nonplanar surfaces including underground lens and cased boreholes are easily treated in a way similar to regular grid points. The Higdon‘s absorbing boundary condition was used to eliminate boundary reflections. Numerical simulations show that the method has satisfactory stability and accuracy. The proposed scheme more efficiently simulates wave propagation in heterogeneous anisotropic media than conventional methods using regular rectangular grids of equal accuracy.  相似文献   
7.
Based on the idea of the reduction of optimal control systems in singularperturbations of Lions and a priori estimates in [4], we prove the convergence of theoptimal control, state and the cost function between a singular linear elastodynamic systemand a limit system. Our asymptotic analysis is applicable to the optimal control of flexiblerobotic manipulators.  相似文献   
8.
The non-orthogonal localized molecular orbital(NOLMO)is the most localized representation of electronic degrees of freedom.As such,NOLMOs are thus potentially the most efficient for linear scaling calculations of electronic structures for large systems.However,direct ab initio calculations with NOLMO have not been fully implemented and widely used,partly because of the slow convergence issue in the optimization of NOLMO.We devel-  相似文献   
9.
【目的】为给海上污染物的清除提供技术支持,应用Radarsat-2全极化数据和均值阈值法对海上油膜及浒苔的提取进行研究。【方法】利用图像分割求取后向散射系数(NRCS)均值d,并用d除以重采样(10*10)平均值得比值t,再根据t值选取得到油膜或浒苔的最小阈值,从而快速识别油膜或浒苔(悬浮与漂浮)面积。【结果】该方法提取油膜所得结果好于熵方法;提取悬浮及漂浮浒苔结果与熵方法、平均Alpha角方法所得结果吻合。【结论】该方法对海上油膜和浒苔的提取有效。  相似文献   
10.
Carbon nitride films are deposited on Si (001) substrates by reactive dc magnetron sputtering graphite in a pure N2 discharge. The structure of carbon nitride films has been probed using Fourier transformation infrared, near edge X-ray absorption fine structure (NEXAFS) and high resolution electron microscopy (HREM), and the hardness has been evaluated in nanoin-dentation experiments. FTIR spectra show that N atoms are bound to sp1, sp2, and sp3 hybridized C atoms. C1s NEXAFS spectra show that the intensity of π* resonance is the lowest for the film grown at substrate temperature TS = 350℃, with a turbostratic-like structure and high hardness, while it is the highest for the film grown at TS = 100℃, with an amorphous structure and low hardness. The correlation between the structure and hardness of carbon nitride films has been discussed.  相似文献   
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