Cellular location of adrenergic amines in frog sympathetic ganglia

Zusammenfassung Die Lokalisation von Adrenalin in den sympathischen Ganglien (Frosch) wird mit Hilfe einer histo-fluorometrischen Methode untersucht. Es konnte Fluoreszenz in zahlreichen Zellen des Ganglions und in den aus den Zellen austretenden Axonen festgestellt werden. Fluoreszierende Nerven, die in Ganglien-Zellen eintreten, wurden nicht beobachtet, so dass die Fluoreszenz auf Adrenalin zurückzuführen sein dürfte.

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The investigation has been supported by a grant from the Swedish Medical Research Council (No. B67-12-714-03) and Magn. Bargvalls Stiftelse, Stockholm, Sweden. The project was undertaken while one of the authors (R.M.) was visiting the Karolinska Institutet under a Special Fellowship N1-F3-GM-6506-01 from the National Institutes of Health (U.S.P.H.).     

Effects of repeated administration ofdl -amphetamine and methamphetamine on tolerance to hyperactivity

Résumé Cette étude concerne le dévelopment d'une accoutumance de l'activité motrice chez les animaux qui ont été traités avec de la méthamphétamine ou avec ladl-amphétamine. Nos résultats indiquent qu'il n'y a pas d'accoutumance chez les animaux qui ont été traités dedl-amphétamine ou de la méthamphétamine.

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This research was supported in part by U.S. Public Health Service Grant No. MH-12959.     

Nitrate flux in the Mississippi River.

Increased delivery of biologically available nitrogen to estuaries and coastal oceans in recent decades has been linked to eutrophication and seasonal hypoxia in the northern Gulf of Mexico and elsewhere. We have developed a model that accounts for 95% of annual variation in delivery of nitrate to the Gulf of Mexico by the Mississippi River in 1960-98. Retrospective analysis indicates that this nitrate flux could have been reduced by 33% if the use of nitrogen-containing fertilizer in the Mississippi River basin had been cut by 12%.