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德力 《内蒙古大学学报(自然科学版)》2004,35(3):260-261
Sauer引理是统计学习理论中的基本结论.在许多实际问题中,需要研究N类模式识别问题.本文将Sauer引理推广到N类分类问题. 相似文献
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乙醇三维内微肋热管的传热性能 总被引:4,自引:0,他引:4
采用实验研究的方法对三维内微肋热管的强化传热特性进行研究,首次报道了以乙醇为工质的三维内微肋热管的传热性能。在实验范围内,与光管相比,竖直放置时,沸腾换热系数可以提高98%—190%,凝结换热系数可以提高76%—178%。三维内微肋结构能够同时明显地强化热管的沸腾换热与凝结换热,可以有效地减小热管的内热阻。 相似文献
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由于风电、光电出力具有不确定性,因此会引起电网频率的较大波动,严重影响电能质量.为了保证含有新能源电力系统的稳定运行,特提出风光水储联合调度优化模型.首先,建立含新能源的电力系统优化调度数学模型,该模型追求系统机组耗量最小.在进行含新能源发电的电力系统优化调度中,可被用来调度的出力实际为满足负荷功率后,扣除新能源输出功率的那部分火电机组出力.算例结果表明,本文采取CVaR具有良好的性能;风电与光伏清洁能源机组并入系统中增加了日前调度的不确定性风险,但通过CVaR评估计算系统风险,采取有效的措施会使系统发电成本减少与碳排放量减少. 相似文献
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Two canids, Vulpes vulpes and Canis lupus , are recorded from shoreline deposits of Lake Bonneville in north central Utah. Both species are new records in the Pleistocene sediments of Utah and add to our scarce knowledge of the large carnivores that inhabited the shoreline environments of Lake Bonneville. 相似文献
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Long Memory of Financial Time Series and Hidden Markov Models with Time‐Varying Parameters
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Hidden Markov models are often used to model daily returns and to infer the hidden state of financial markets. Previous studies have found that the estimated models change over time, but the implications of the time‐varying behavior have not been thoroughly examined. This paper presents an adaptive estimation approach that allows for the parameters of the estimated models to be time varying. It is shown that a two‐state Gaussian hidden Markov model with time‐varying parameters is able to reproduce the long memory of squared daily returns that was previously believed to be the most difficult fact to reproduce with a hidden Markov model. Capturing the time‐varying behavior of the parameters also leads to improved one‐step density forecasts. Finally, it is shown that the forecasting performance of the estimated models can be further improved using local smoothing to forecast the parameter variations. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
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物料分选过程 ,是整个体系能量降低的过程 ,从这一原理出发 ,不同性质的固体颗粒在重介质旋流器中将位于不同的位置 ,使不同性质的固体颗粒得以分离。固体颗粒在重介质旋流器中的运动轨迹大体呈圆锥螺旋线形状 ,实测出的密度线验证了该结论 相似文献
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A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor 总被引:14,自引:0,他引:14
Madsen LS Andersson EC Jansson L krogsgaard M Andersen CB Engberg J Strominger JL Svejgaard A Hjorth JP Holmdahl R Wucherpfennig KW Fugger L 《Nature genetics》1999,23(3):343-347
Multiple sclerosis (MS) is a complex chronic neurologic disease with a suspected autoimmune pathogenesis. Although there is evidence that the development of MS is determined by both environmental influences and genes, these factors are largely undefined, except for major histocompatibility (MHC) genes. Linkage analyses and association studies have shown that susceptibility to MS is associated with genes in the human histocompatibility leukocyte antigens (HLA) class II region, but the contribution of these genes to MS disease development less compared with their contribution to disorders such as insulin-dependent diabetes mellitus. Due to the strong linkage disequilibrium in the MHC class II region, it has not been possible to determine which gene(s) is responsible for the genetic predisposition. In transgenic mice, we have expressed three human components involved in T-cell recognition of an MS-relevant autoantigen presented by the HLA-DR2 molecule: DRA*0101/DRB1*1501 (HLA-DR2), an MHC class II candidate MS susceptibility genes found in individuals of European descent; a T-cell receptor (TCR) from an MS-patient-derived T-cell clone specific for the HLA-DR2 bound immunodominant myelin basic protein (MBP) 4102 peptide; and the human CD4 coreceptor. The amino acid sequence of the MBP 84-102 peptide is the same in both human and mouse MBP. Following administration of the MBP peptide, together with adjuvant and pertussis toxin, transgenic mice developed focal CNS inflammation and demyelination that led to clinical manifestations and disease courses resembling those seen in MS. Spontaneous disease was observed in 4% of mice. When DR2 and TCR double-transgenic mice were backcrossed twice to Rag2 (for recombination-activating gene 2)-deficient mice, the incidence of spontaneous disease increased, demonstrating that T cells specific for the HLA-DR2 bound MBP peptide are sufficient and necessary for development of disease. Our study provides evidence that HLA-DR2 can mediate both induced and spontaneous disease resembling MS by presenting an MBP self-peptide to T cells. 相似文献