全文获取类型
收费全文 | 4363篇 |
免费 | 27篇 |
国内免费 | 62篇 |
专业分类
系统科学 | 27篇 |
丛书文集 | 83篇 |
教育与普及 | 64篇 |
理论与方法论 | 5篇 |
现状及发展 | 1974篇 |
研究方法 | 199篇 |
综合类 | 2088篇 |
自然研究 | 12篇 |
出版年
2012年 | 57篇 |
2011年 | 86篇 |
2010年 | 38篇 |
2009年 | 104篇 |
2008年 | 87篇 |
2007年 | 117篇 |
2006年 | 71篇 |
2005年 | 117篇 |
2004年 | 130篇 |
2003年 | 83篇 |
2002年 | 83篇 |
2001年 | 218篇 |
2000年 | 193篇 |
1999年 | 141篇 |
1998年 | 32篇 |
1997年 | 28篇 |
1996年 | 21篇 |
1995年 | 30篇 |
1992年 | 104篇 |
1991年 | 90篇 |
1990年 | 92篇 |
1989年 | 70篇 |
1988年 | 78篇 |
1987年 | 80篇 |
1986年 | 59篇 |
1985年 | 98篇 |
1984年 | 81篇 |
1983年 | 62篇 |
1982年 | 65篇 |
1981年 | 59篇 |
1980年 | 75篇 |
1979年 | 146篇 |
1978年 | 134篇 |
1977年 | 107篇 |
1976年 | 79篇 |
1975年 | 73篇 |
1974年 | 98篇 |
1973年 | 103篇 |
1972年 | 89篇 |
1971年 | 111篇 |
1970年 | 100篇 |
1969年 | 96篇 |
1968年 | 95篇 |
1967年 | 87篇 |
1966年 | 86篇 |
1965年 | 58篇 |
1959年 | 24篇 |
1958年 | 41篇 |
1957年 | 32篇 |
1956年 | 29篇 |
排序方式: 共有4452条查询结果,搜索用时 31 毫秒
1.
杨建荣 《科技情报开发与经济》2004,14(6):157-158
根据我国当前电力系统运行情况,对电网无功功率补偿的必要性及通用补偿方法及其装置进行了具体阐述。 相似文献
2.
西文期刊回溯建库中几个重要项目的著录 总被引:4,自引:0,他引:4
在实践的基础上,从期刊的出版日期、出版周期、卷、期、年、月及其他标识、ISSN、增刊、出版者以及期刊的历史发展等方面对西文期刊机读目录的标准化著录问题进行了探讨。 相似文献
3.
王永红 《科技情报开发与经济》2004,14(6):139-141
通过1998年、2000年的试验研究,系统分析了顶凌覆盖技术在高寒区节水增温保温、增产增收的机理及其应用效果。提出该技术可以缓解低温干旱特别是春旱对农业生产的困扰,是一项可以抗旱保春播增产增收的实用技术,在高寒地区具有较高的推广价值。 相似文献
4.
Y Y He T McNally I Manfield O Navratil I G Old S E Phillips I Saint-Girons P G Stockley 《Nature》1992,359(6394):431-433
The three-dimensional crystal structure of the Escherichia coli methionine repressor, MetJ, complexed with a DNA operator fragment is described in an accompanying article. The complex exhibits several novel features of DNA-protein interaction. DNA sequence recognition is achieved largely by hydrogen-bond contacts between the bases and amino-acid side chains located on a beta-ribbon, a mode of recognition previously hypothesized on the basis of modelling of idealized beta-strands and DNA, and mutagenesis of the Salmonella phage P22 repressors Arc and Mnt. The complex comprises a pair of MetJ repressor dimers which bind to adjacent met-box sites on the DNA, and contact each other by means of a pair of antiparallel alpha-helices. Here we assess the importance of these contacts, and also of contacts that would be made between the C-helices of the protein and DNA in a previous model of the complex, by studying mutations aimed at disrupting them. The role of the carboxy-terminal helix face in operator binding was unclear, but we demonstrate that recognition of operator sequences occurs through side chains in the beta-strand motif and that dimer-dimer interactions are required for effective repression. 相似文献
5.
Vitamin B12 (methylcobalamin) was administered orally (3 mg/day) to 9 healthy subjects for 4 weeks. Nocturnal melatonin levels after exposure to bright light (ca. 2500 lx) were determined, as well as the levels of plasma melatonin over 24 h. The timing of sleep was also recorded. Vitamin B12 was given blind to the subjects and crossed over with placebo. We found that the 24-h melatonin rhythm was significantly phase-advanced (1.1 h) in the vitamin B12 trial as compared with that in the placebo trial. In addition, the 24-h mean of plasma melatonin level was much lower in the vitamin B12 trial than with the placebo. Furthermore, the nocturnal melatonin levels during bright light exposure were significantly lower in the vitamin B12 trial than with the placebo. On the other hand, vitamin B12 did not affect the timing of sleep. These findings raise the possibility that vitamin B12 phase-advances the human circadian rhythm by increasing the light sensitivity of the circadian clock. 相似文献
6.
Kang J.Y. Xu F.C. 《中国科学基金(英文版)》2004,(2):57-58,64
1 Introduction
Nanoscale science and technology have attracted greatattention since the novel properties become dominant for well-known materials as their sizes reduced to some critical dimension. These properties frequently originate in lattice distortions, structure transformations etc[1]. The variations of size and structure ofnanocrystals lead to the change of their electronic structures. Very recently, nanoscale materials with different electronic structures were utilized in fabricating nanoscale junctions[2].
…… 相似文献
7.
It is well known that transmitter secretion requires specialized secretory organelles, the synaptic vesicles, for the packaging, storage and exocytotic release of the transmitter. Here we report that when acetylcholine (ACh) is loaded into an isolated Xenopus myocyte, there is spontaneous quantal release of ACh from the myocyte which results in activation of its own surface ACh channels and the appearance of membrane currents resembling miniature endplate currents. This myocyte secretion probably reflects Ca(2+)-regulated exocytosis of ACh-filled cytoplasmic compartments. Furthermore, step depolarization of the myocyte membrane triggers evoked ACh release from the myocyte with a weak excitation-secretion coupling. These findings suggest that quantal transmitter secretion does not require secretory pathways unique to neurons and that the essence of presynaptic differentiation may reside in the provision of transmitter supply and modification of the preexisting secretion pathway. 相似文献
8.
A. F. McDonagh Y. -M. Pu D. A. Lightner 《Cellular and molecular life sciences : CMLS》1992,48(3):246-248
The characteristic circular dichroism of bilirubin bound to human serum albumin undergoes a remarkable sign inversion on addition of halothane, chloroform and other volatile anesthetics. This sign inversion, which is completely reversed by removal of the anesthetic, reflects a pronounced conformational change of the bound ligand; probably a complete inversion of chirality. The observation suggests that association of volatile anesthetics with proteins can markedly alter the internal topography of receptor sites and potentially influence the stereoselectivity of ligand binding. 相似文献
9.
The timing of sleep and sleep EEG parameters in 10 healthy male subjects were investigated in four seasons under controlled conditions. The phase of nocturnal sleep was delayed about one and a half hours in winter as compared to that in summer. The duration of stage 4 sleep decreased and REM sleep increased significantly in winter compared with summer. The seasonality in the timing of sleep can be explained by photoperiodic time cues, but the changes in sleep EEG parameters are difficult to explain in terms of photoperiod. 相似文献
10.
Summary Host cell reactivation capacity for ozone T3 phage was determined for differentE. coli strains deficient in one or more of the DNA repair mechanisms. The results indicate that DNA polymerase I appears to play a key role in the repair of damage produced on the DNA by ozone while thelexA gene product seems to play a minor one.This research was sponsored by the National Sciences and Engineering Council of Canada. One of us (PLH) acknowledges a scholarship from the NSERCof Canada. 相似文献