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1.
Synthesis of infectious phiX-174 bacteriophage in vitro   总被引:6,自引:0,他引:6  
R Mukai  M Hayashi 《Nature》1977,270(5635):364-366
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2.
K Kajiwara  L B Hahn  S Mukai  G H Travis  E L Berson  T P Dryja 《Nature》1991,354(6353):480-483
The murine retinal degeneration slow (rds) gene is a semidominant mutation with a phenotype having rod and cone photoreceptors that develop abnormally and then slowly degenerate. The phenotype is a possible model for retinitis pigmentosa, one of the scores of hereditary human retinal degenerations, which is also characterized by photoreceptor degeneration. We report here three mutations of the human homologue of the rds gene (RDS) that cosegregate with autosomal dominant retinitis pigmentosa in separate families. Our results indicate that some cases of autosomal dominant retinitis pigmentosa are due to mutations at the RDS locus.  相似文献   
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Sokoloski JL  Luna GJ  Mukai K  Kenyon SJ 《Nature》2006,442(7100):276-278
Stellar explosions such as novae and supernovae produce most of the heavy elements in the Universe. The onset of a nova is well understood as driven by runaway thermonuclear fusion reactions on the surface of a white dwarf in a binary star system; but the structure, dynamics and mass of the ejecta are not well known. In rare cases, the white dwarf is embedded in the wind nebula of a red-giant companion, and the explosion products plough through the nebula and produce X-ray emission. Here we report X-ray observations of such an event, from the eruption of the recurrent nova RS Ophiuchi. The hard X-ray emission from RS Ophiuchi early in the eruption emanates from behind a blast wave, or outward-moving shock wave, that expanded freely for less than 2 days and then decelerated owing to interaction with the nebula. The X-rays faded rapidly, suggesting that the blast wave deviates from the standard spherical shell structure. The early onset of deceleration indicates that the ejected shell had a low mass, the white dwarf has a high mass, and that RS Ophiuchi is therefore a progenitor of the type of supernova (type Ia) integral to studies of the expansion of the Universe.  相似文献   
5.
Magnetic reconnection is a process that converts magnetic energy into bi-directional plasma jets; it is believed to be the dominant process by which solar-wind energy enters the Earth's magnetosphere. This energy is subsequently dissipated by magnetic storms and aurorae. Previous single-spacecraft observations revealed only single jets at the magnetopause--while the existence of a counter-streaming jet was implicitly assumed, no experimental confirmation was available. Here we report in situ two-spacecraft observations of bi-directional jets at the magnetopause, finding evidence for a stable and extended reconnection line; the latter implies substantial entry of the solar wind into the magnetosphere. We conclude that reconnection is determined by large-scale interactions between the solar wind and the magnetosphere, rather than by local conditions at the magnetopause.  相似文献   
6.
Reversible phase transitions in polymer gels induced by radiation forces   总被引:2,自引:0,他引:2  
Juodkazis S  Mukai N  Wakaki R  Yamaguchi A  Matsuo S  Misawa H 《Nature》2000,408(6809):178-181
Many polymer gels undergo reversible, discontinuous volume changes in response to changes in the balance between repulsive intermolecular forces that act to expand the polymer network and attractive forces that act to shrink it. Repulsive forces are usually electrostatic or hydrophobic in nature, whereas attraction is mediated by hydrogen bonding or van der Waals interactions. The competition between these counteracting forces, and hence the gel volume, can thus be controlled by subtle changes in parameters such as pH (ref. 4), temperature, solvent composition or gel composition. Here we describe a more direct influence on this balance of forces, by showing that the radiation force generated by a focused laser beam induces reversible shrinkage in polymer gels. Control experiments confirm that the laser-induced volume phase transitions are due to radiation forces, rather than local heating, modifying the weak interactions in the gels, in agreement with previous observations of light-induced chain association in polymer solutions. We find that, owing to shear-relaxation processes, gel shrinkage occurs up to several tens of micrometres away from the irradiation spot, raising the prospect that the combination of stimuli-responsive polymer gels and laser light might lead to new gel-based systems for applications such as actuating or sensing.  相似文献   
7.
The earthquake-triggered landslides and slope failures are common phenomena during strong earthquakes and have drawn more attention from the world because of severe hazards they induced. These hazards usually cannot be prevented by current mitigating measures, thus, it becomes more and more important to develop a precise technique for the risk assessment of earthquake-induced failures in the mountainous area. The application of discrimination analysis method is proved to be successful and effective in the prediction of earthquake-triggered landslides and slope failures in the region of Imokawa Basin in Japan. Discriminant score can be used to assess the relative risk of slope failures, as the score increases, the possibility of slope failures occurrence increases accordingly. At the same time, the variables in the judgement formula, such as slope gradient, slope curvature and seismic peak ground acceleration, are easy to obtain. This advantage makes this method more practical and manipulable than others at present. In order to apply this method more effectively, there are still several problems to resolve.  相似文献   
8.
Most visible matter in the Universe exists as plasma. How this plasma is heated, and especially how the initial non-equilibrium plasma distributions relax to thermal equilibrium (as predicted by Maxwell-Boltzman statistics), is a fundamental question in studies of astrophysical and laboratory plasmas. Astrophysical plasmas are often so tenuous that binary collisions can be ignored, and it is not clear how thermal equilibrium develops for these 'collisionless' plasmas. One example of a collisionless plasma is the Earth's plasma sheet, where thermalized hot plasma with ion temperatures of about 5 x 10(7) K has been observed. Here we report direct observations of a plasma distribution function during a solar eclipse, revealing cold ions in the Earth's plasma sheet in coexistence with thermalized hot ions. This cold component cannot be detected by plasma sensors on satellites that are positively charged in sunlight, but our observations in the Earth's shadow show that the density of the cold ions is comparable to that of hot ions. This high density is difficult to explain within existing theories, as it requires a mechanism that permits half of the source plasma to remain cold upon entry into the hot turbulent plasma sheet.  相似文献   
9.
The massive flare of 27 December 2004 from the soft gamma-ray repeater SGR 1806-20, a possible magnetar, saturated almost all gamma-ray detectors, meaning that the profile of the pulse was poorly characterized. An accurate profile is essential to determine physically what was happening at the source. Here we report the unsaturated gamma-ray profile for the first 600 ms of the flare, with a time resolution of 5.48 ms. The peak of the profile (of the order of 10(7) photons cm(-2) s(-1)) was reached approximately 50 ms after the onset of the flare, and was then followed by a gradual decrease with superposed oscillatory modulations possibly representing repeated energy injections with approximately 60-ms intervals. The implied total energy is comparable to the stored magnetic energy in a magnetar (approximately 10(47) erg) based on the dipole magnetic field intensity (approximately 10(15) G), suggesting either that the energy release mechanism was extremely efficient or that the interior magnetic field is much stronger than the external dipole field.  相似文献   
10.
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