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Pineal gland changes of rats exposed to heat   总被引:1,自引:0,他引:1  
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本对新疆南、北疆、东疆地区和乌鲁木齐市的101所民族中学进行实地的调查研究,通过对各民族中学体育教学中大纲、教材、场地器材、汉语授课、男女生分班情况、教师培训、教学计划以及对课程改革的认识等方面的分析.进一步了解新疆各地区民族中学学校体育状况,特别是“体育与健康”课程实施后,各地区民族中学学校体育教学现状以及所面临的问题,旨在加快新疆少数民族中学的体育教学改革和《体育与健康》课程教学研究。为新疆教育主管部门制定实施“体育与健康”课程教学提供决策依据。  相似文献   
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Summary Exposure of adult male rats to continuously elevated temperature of 32–34°C caused a significant decrease of HIOMT activity involved in the specific metabolic process of production of melatonin, considered an active pineal hormone. The effect was already evident after 24 h exposure and increased further during the next 48 h. The results obtained substantiate previous data that the pineal gland may be involved in the system regulating adaptation to extreme temperature changes.Acknowledgment. The authors are indebted to MissUte Schmidt for her excellent technical assistance.  相似文献   
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Summary Exposure of adult male rats to increased temperature of 33±1°C for 3 and 10 days brought about decreases in pineal N-acetyltransferase activity. These and previous findings of pineal HIOMT inhibition under similar conditions support the postulation of a possible thermoregulatory role for the pineal gland.  相似文献   
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Asmerom Y  Cheng H  Thomas R  Hirschmann M  Edwards RL 《Nature》2000,406(6793):293-296
The processes responsible for the generation of partial melt in the Earth's lithospheric mantle and the movement of this melt to the Earth's surface remain enigmatic, owing to the perceived difficulties in generating large-degree partial melts at depth and in transporting small-degree melts through a static lithosphere. Here we present a method of placing constraints on melting in the lithospheric mantle using 231Pa-235U data obtained from continental basalts in the southwestern United States and Mexico. Combined with 230Th-238U data, the 231Pa-235U data allow us to constrain the source mineralogy and thus the depth of melting of these basalts. Our analysis indicates that it is possible to transport small melt fractions--of the order of 0.1%--through the lithosphere, as might result from the coalescence of melt by compaction owing to melting-induced deformation. The large observed 231Pa excesses require that the timescale of melt generation and transport within the lithosphere is small compared to the half-life of 231Pa (approximately 32.7 kyr). The 231Pa-230Th data also constrain the thorium and uranium distribution coefficients for clinopyroxene in the source regions of these basalts to be within 2% of one another, indicating that in this setting 230Th excesses are not expected during melting at depths shallower than 85 km.  相似文献   
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A new class of angiotensin-converting enzyme inhibitors   总被引:22,自引:0,他引:22  
Much current attention focuses on the renin-angiotensin system in relation to mechanisms controlling blood pressure and renal function. Recent demonstrations (ref. 1, ref. 2 and refs therein) that angiotensin-converting enzyme inhibitors show promising clinical antihypertensive properties have been of particular interest. We now report on the design of a novel series of substituted N-carboxymethyl-dipeptides which are active in inhibiting angiotensin-converting enzyme at nanomolar levels. We suggest that these compounds are transition-state inhibitors and that extensions of this design to other metalloendopeptidases merit further study.  相似文献   
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Exposure of adult male rats to continuously elevated temperature of 32-34 degrees C caused a significant decrease of HIOMT activity involved in the specific metabolic process of production of melatonin, considered an active pineal hormone. The effect was already evident after 24 h exposure and increased further during the next 48 h. The results obtained substantiate previous data that the pineal gland may be involved in the system regulating adaptation to extreme temperature changes.  相似文献   
10.
Melting in the Earth's deep upper mantle caused by carbon dioxide   总被引:5,自引:0,他引:5  
Dasgupta R  Hirschmann MM 《Nature》2006,440(7084):659-662
The onset of partial melting beneath mid-ocean ridges governs the cycling of highly incompatible elements from the mantle to the crust, the flux of key volatiles (such as CO2, He and Ar) and the rheological properties of the upper mantle. Geophysical observations indicate that melting beneath ridges begins at depths approaching 300 km, but the cause of this melting has remained unclear. Here we determine the solidus of carbonated peridotite from 3 to 10 GPa and demonstrate that melting beneath ridges may occur at depths up to 330 km, producing 0.03-0.3% carbonatite liquid. We argue that these melts promote recrystallization and realignment of the mineral matrix, which may explain the geophysical observations. Extraction of incipient carbonatite melts from deep within the oceanic mantle produces an abundant source of metasomatic fluids and a vast mantle residue depleted in highly incompatible elements and fractionated in key parent-daughter elements. We infer that carbon, helium, argon and highly incompatible heat-producing elements (such as uranium, thorium and potassium) are efficiently scavenged from depths of approximately 200-330 km in the upper mantle.  相似文献   
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