Effect of detoxin D on blasticidin S uptake inBacillus cereus

Summary The active transport of blasticidin S into the cells ofBacillus cereus was significantly inhibited by the addition of detoxin D or poisons of energy metabolism.The authors are grateful to Prof. M. Matsuhashi of our Institute for his valuable advice and to Dr I. Yamaguchi, Institute of Physical and Chemical Research, for the gift of labeled blasticidin S. This work is supported in part by a grant from the Ministry of Education, Science and Culture, Government of Japan.This is Part VII of Studies on Detoxin Complex, the Selective Anatagonists of Blasticidin S. For Part VI, see the preceding report.