Unusual sugar biosynthesis and natural product glycodiversification

The enzymes involved in the biosynthesis of carbohydrates and the attachment of sugar units to biological acceptor molecules catalyse an array of chemical transformations and coupling reactions. In prokaryotes, both common sugar precursors and their enzymatically modified derivatives often become substituents of biologically active natural products through the action of glycosyltransferases. Recently, researchers have begun to harness the power of these biological catalysts to alter the sugar structures and glycosylation patterns of natural products both in vivo and in vitro. Biochemical and structural studies of sugar biosynthetic enzymes and glycosyltransferases, coupled with advances in bioengineering methodology, have ushered in a new era of drug development.     

使用除法算法对里德-所罗门编码进行解码

里德-所罗门编码是最广泛使用的纠错码之一.介绍一种使用除法算法的解码方法,发展该算法的理论并讨论支持该算法的例子.最后,证明与该解码算法有关的一个概率上的定理,关于何时该方法是最有效的,得出一些概率上的结果.