复线电气化区段施工感应电对人体的危害及防护对策

感应电会对人体造成伤害。从电磁感应和静电感应原理入手，分析了产生感应电的过程，并就如何防止感应电的危害提出了防护对策，有一定实用价值。     

链条炉存在的问题及解决方法

从炉排横向配风不均、风室压火、煤层厚度阻力及锅炉燃烧等方面分析了链条锅炉存在的问题，并针对存在的问题提出了相应的解决办法。     

对提高施工中光缆接续质量的探讨

通过分析影响光缆接续质量的因素，从减少本征影响、克服技术因素、优化综合处置、减弱和避开环境影响4方面针对性地提出了实际施工中应采取的施工方法，以控制和减小不利影响，提高光缆工程的接续质量，为建设高质量传输线路提供有力保证。     

巧用Visual FoxPro制作套表打印

从报表创建、报表布局及打印调试等方面介绍了利用Visual FoxPro的快速报表实现套表打印的具体操作步骤。在Visual FoxPro下制作报表简单、实用、方便，很好地解决了数据套表打印问题。     

24吨翻卷机液压系统设计

通过对２４吨翻卷机液压驱动与控制系统的设计与研究，提出了一种全新的适合于重载翻转负荷的插装控制回路系统．它具有通流量大、压力损失小、成本低、能耗少、发热低等优点     

为构建“和谐河北“营造和谐的舆论环境——新形势下新闻宣传深层思考

构建“和谐河北”是中央提出的构建社会主义和谐社会在我省的具体实践,加强对构建“和谐河北”舆论宣传的调查、理论研究,已成为河北省新闻宣传界重大的理论与实践课题。为构建“和谐河北”营造和谐的舆论环境,河北省新闻宣传工作的重点应放在以下四个方面:坚持以正确的舆论引导人,坚定把握宣传基调不动摇;提升舆论引导水平,理性探求和谐社会矛盾的化解思路;增强舆论影响能力,形成构建“和谐河北”的舆论强势;清醒把握舆论导向,消除宣传报道中的不和谐音符等。     

《税务管理》课程体系建设研究

《税务管理》课程是专业调整后财政、税务专业本、专科必修课程之一,该课程以国家税收政策、法规为依据,具有很强的可操作性。为提高教学效果,本文就该课程的教学内容、教学方法、教学手段等进行了有益的探索。     

预应力混凝土平面曲线箱梁裂缝

针对预应力混凝土曲线箱梁,产生径向水平压力的平面曲线力筋易使混凝土腹板超载,而造成混凝土破坏,并使力筋拉直等问题,应用翘曲扭转理论,分析了预应力混凝土平面曲线箱梁在张拉平面曲线形纵向力筋时,将在腹板中产生横向力,以及桥墩和桥梁支座约束作用,局部板中力筋的径向力使竖向跨越的腹板产生剪力和弯矩等产生裂缝的原因,提出了在设计与施工中应采取保证力筋的保护层厚度,充分调整力筋曲率的作用,设计计算必须考虑侧向预应力,保证在力筋弯曲的部位、管道不出现尖弯等措施。为平面曲线桥梁的设计与施工提供了一定的理论依据。     

A second generation human haplotype map of over 3.1 million SNPs

We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25-35% of common SNP variation in the populations surveyed. The map is estimated to capture untyped common variation with an average maximum r2 of between 0.9 and 0.96 depending on population. We demonstrate that the current generation of commercial genome-wide genotyping products captures common Phase II SNPs with an average maximum r2 of up to 0.8 in African and up to 0.95 in non-African populations, and that potential gains in power in association studies can be obtained through imputation. These data also reveal novel aspects of the structure of linkage disequilibrium. We show that 10-30% of pairs of individuals within a population share at least one region of extended genetic identity arising from recent ancestry and that up to 1% of all common variants are untaggable, primarily because they lie within recombination hotspots. We show that recombination rates vary systematically around genes and between genes of different function. Finally, we demonstrate increased differentiation at non-synonymous, compared to synonymous, SNPs, resulting from systematic differences in the strength or efficacy of natural selection between populations.     

Genome-wide detection and characterization of positive selection in human populations

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and we also developed new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population. The analysis reveals more than 300 strong candidate regions. Focusing on the strongest 22 regions, we develop a heuristic for scrutinizing these regions to identify candidate targets of selection. In a complementary analysis, we identify 26 non-synonymous, coding, single nucleotide polymorphisms showing regional evidence of positive selection. Examination of these candidates highlights three cases in which two genes in a common biological process have apparently undergone positive selection in the same population:LARGE and DMD, both related to infection by the Lassa virus, in West Africa;SLC24A5 and SLC45A2, both involved in skin pigmentation, in Europe; and EDAR and EDA2R, both involved in development of hair follicles, in Asia.