Geochemistry of Clayey Aquitard Pore Water as Archive of Paleo-Environment,Western Bohai Bay

The record of paleo-environment in clayey aquitard pore water is much more effective relative to aquifer groundwater owing to the low permeability of clayey aquitard. Oxygen-18 (18O), deuterium (D), an...     

浅谈功率因数的补偿及其应用

根据我国当前电力系统运行情况，对电网无功功率补偿的必要性及通用补偿方法及其装置进行了具体阐述。     

西文期刊回溯建库中几个重要项目的著录

在实践的基础上，从期刊的出版日期、出版周期、卷、期、年、月及其他标识、ISSN、增刊、出版者以及期刊的历史发展等方面对西文期刊机读目录的标准化著录问题进行了探讨。     

顶凌覆盖节水增产技术研究

通过1998年、2000年的试验研究，系统分析了顶凌覆盖技术在高寒区节水增温保温、增产增收的机理及其应用效果。提出该技术可以缓解低温干旱特别是春旱对农业生产的困扰，是一项可以抗旱保春播增产增收的实用技术，在高寒地区具有较高的推广价值。     

钢纤维混凝土桥面铺装试验研究与工程应用

针对桥面铺装层的受力状况和破坏原因 ,重点对钢纤维砼材料进行了抗弯强度试验和耐磨损试验 ,并进行了钢纤维砼弯曲性能分析 ,闸述了钢纤维砼的耐磨机理 ;结合 130 76m2 的实际工程应用 ,进行了钢纤维砼桥面铺装施工技术总结 ,分析了采用钢纤维砼作为桥面铺装层所带来的效益 ,可供类似工程参考应用     

浅谈城市夜景照明管理

文章阐述了城市夜景照明存在的不足，从五个方面提出今后的发展思路。     

一种基于粗集理论的属性权重构造方法

提出一种新的基于粗集理论的权重构造方法来解决传统决策中主观性问题和冗余性问题,并给出了一种新的判据模式.新方法分析论述了可拓学中存在的数学逻辑错误,并与通过其他决策方法得出的结论作比较.最终通过实验分析来说明方法的有效性和可行性,从而为管理决策提供了一种新的思想.     

神经网络在电磁场数值问题中的应用

针对目前电磁场数值处理中计算繁杂慢速和耗费资源过多的问题,本文提出了一种基于神经网络小波理论进行计算的新方法。文中着重介绍了利用小波变换神经网络的基本理论,结合电磁场数值计算的基本方法,推导变换进而得到一个通用公式和处理方法。在该方法中,神经网络学习内容少和数据处理简单,因此该方法具有计算速度快,占用资源少的优点,并有用硬件实现的前景。     

Therapeutic applications of bone marrow-derived stem cells in liver transplantation for end-stage liver diseases

Today, liver transplantation (LT) is the only established treatment for end-stage liver diseases. The de- velopment of LT, including OLT, cadaveric LT, split LT, living donor LT (LDLT), brings hopes to patients with these diseases. However, increasing donor shortage, rejection and life-long immunosuppression with its side effects are the major limitations of this therapy strategy. Bone marrow-derived stem cells (BMDSCs) are capable of differentiating into hepatocyte-like cells and contribute to liver injury repair. The microenvironment of liver injury caused by rejection, ischemia/reperfusion, loss of liver mass, recurrence of HCV and "small-for-size syndrome" after LT can attract a variety of bone marrow-derived stem cell population to the peripheral circulation and then migration to the injury liver to promote the hepatic function restoration. Additionally, BMDSCs can also take part in the functional regeneration of living donor liver after LDLT. This participation in liver regeneration may be associated to the interac- tion between SDF-1and its receptor CXCR4, involving HGF, IL-8, MMP9, and VEGF/VEGFR-2. BMDSC with its bio-characteristics could maintain the allograft tolerance from different angles and in different ways. In conclusion, BMDSCs transplantation, as a new assistant therapeutic method for LT, will ex- pand the space of LT, and provide more survival opportunities for the patients suffering liver diseases in the future.     

Probing met repressor-operator recognition in solution.

The three-dimensional crystal structure of the Escherichia coli methionine repressor, MetJ, complexed with a DNA operator fragment is described in an accompanying article. The complex exhibits several novel features of DNA-protein interaction. DNA sequence recognition is achieved largely by hydrogen-bond contacts between the bases and amino-acid side chains located on a beta-ribbon, a mode of recognition previously hypothesized on the basis of modelling of idealized beta-strands and DNA, and mutagenesis of the Salmonella phage P22 repressors Arc and Mnt. The complex comprises a pair of MetJ repressor dimers which bind to adjacent met-box sites on the DNA, and contact each other by means of a pair of antiparallel alpha-helices. Here we assess the importance of these contacts, and also of contacts that would be made between the C-helices of the protein and DNA in a previous model of the complex, by studying mutations aimed at disrupting them. The role of the carboxy-terminal helix face in operator binding was unclear, but we demonstrate that recognition of operator sequences occurs through side chains in the beta-strand motif and that dimer-dimer interactions are required for effective repression.