基于Agent的农田生态细胞自动机模型

提出一种基于Agent的细胞自动机(CA)演化模型，并采用整体建模仿真的方法，对农田虫害的演化进行了模拟．它采用自底向上的建模思想，利用Agent的局部连接规则，建立复杂系统的整体模型．针对不同环境条件设定相应的仿真参数，可以得到恰当的害虫种群演化结果，有助于农田生态管理的科学决策．同时，农田虫害的管理是预测专家系统的重要应用领域，该模型与专家系统的最终集成，可以提高专家系统的预测能力．     

The role of key residues in structure, function, and stability of cytochrome-c

Cytochrome-c (cyt-c), a multi-functional protein, plays a significant role in the electron transport chain, and thus is indispensable in the energy-production process. Besides being an important component in apoptosis, it detoxifies reactive oxygen species. Two hundred and eighty-five complete amino acid sequences of cyt-c from different species are known. Sequence analysis suggests that the number of amino acid residues in most mitochondrial cyts-c is in the range 104?±?10, and amino acid residues at only few positions are highly conserved throughout evolution. These highly conserved residues are Cys14, Cys17, His18, Gly29, Pro30, Gly41, Asn52, Trp59, Tyr67, Leu68, Pro71, Pro76, Thr78, Met80, and Phe82. These are also known as “key residues”, which contribute significantly to the structure, function, folding, and stability of cyt-c. The three-dimensional structure of cyt-c from ten eukaryotic species have been determined using X-ray diffraction studies. Structure analysis suggests that the tertiary structure of cyt-c is almost preserved along the evolutionary scale. Furthermore, residues of N/C-terminal helices Gly6, Phe10, Leu94, and Tyr97 interact with each other in a specific manner, forming an evolutionary conserved interface. To understand the role of evolutionary conserved residues on structure, stability, and function, numerous studies have been performed in which these residues were substituted with different amino acids. In these studies, structure deals with the effect of mutation on secondary and tertiary structure measured by spectroscopic techniques; stability deals with the effect of mutation on T _m (midpoint of heat denaturation), ?G _D (Gibbs free energy change on denaturation) and folding; and function deals with the effect of mutation on electron transport, apoptosis, cell growth, and protein expression. In this review, we have compiled all these studies at one place. This compilation will be useful to biochemists and biophysicists interested in understanding the importance of conservation of certain residues throughout the evolution in preserving the structure, function, and stability in proteins.     

Stimuli-responsive polymeric materials for human health applications

Stimuli-responsive polymers have the extraor- dinary ability to change their physical and/or chemical state after they ＂detect＂ a change in their environment; their response depends dramatically on their chemical compo- sition. This property has been used for a plethora of applications; this review highlights their utility for human health. Specifically, this review will highlight efforts in the areas of sensing and biosensing, antimicrobial/antifouling coatings, tissue engineering and regenerative medicine, and drug delivery. Specific examples are given in each of these areas, with some focus on our work engineering poly（N- isopropylacrylamide）-based microgels and other respon- sive systems.     

两种消除Klebsiella pneumoniae重组型质粒的方法

对于工业发酵菌种肺炎克雷伯氏菌(Klebsiella pneumoniae),研究发现有两种消除其重组型质粒的有效方法,一种是连续传代培养,另一种是使用消除剂十二烷基硫酸钠(SDS)。对K.pneumoniae重组菌连续20代传代培养后,发现其质粒具有较高的消除率;而以0.2%SDS复合Ca2+处理K.pneumoniae重组菌,也能有效消除其重组型质粒,且该方法省却了反复的传代培养,能快速得到质粒消除菌,更具简便易操作性。消除了质粒的K.pneumoniae能再次接纳新的质粒,有效避免了因质粒不相容性带来的转化不成功,进而可用作宿主菌积累更多的生理性状。     

高位钻孔瓦斯抽采参数优化设计

基于采空区覆岩裂隙分布规律、覆岩裂隙瓦斯流动规律和高位钻孔抽采技术研究现状,从覆岩"竖三带"、"O"形圈和U型通风条件下采动裂隙瓦斯流动规律出发,找出高位钻孔的理论合理布置区域,指出工作面后方50m范围内覆岩裂隙发育状况是高位钻孔层位设计的关键,针对祁南煤矿32煤层的特点,结合现场采用数值模拟方法模拟不同开采速度条件下覆岩裂隙发育规律,优化设计高位钻孔的抽采参数,在34下2工作面和3410工作面的现场试验中,高位钻孔抽采浓度和抽采率得到大大提高,取得了较好的抽采效果,验证了研究的正确性。     

非线性映象的Mann迭代的收敛性与不动点

在可度量化拓扑线性空间中，讨论一些非线性映象的不动点与Mann迭代序列的收敛性问题，在一定条件下，得到了一些新的结果，推广和发展了Khan,Ghosh及Rhoades等人的工作。     

导出矩阵与基底的正交化

给出导出矩阵的概念并利用它将Ｒｎ中任意一组基底正交化     

Evidence for possible emergence of immunochemically distinct nucleotide-peptides in malignant transformation.

Antibodies against nucleotide-peptides of beef heart do crossreact with nucleotide-peptides of other beef organs, but with nucleotide-peptides of Ehrlich tumor cells. Antibodies against the latter do not crossreact with nucleotide-peptides of normal organs, but do so with nucleotide-peptides of a rat hepatoma.     

导出矩阵与基底的正交化

给出导出矩阵的概念并利用它将Rn中任意一组基底正交化.     

二甲基亚砜中Dy和Co的电化学行为

利用循环伏安法和计时电流法研究了室温下Dy和Co在二甲基亚砜中的电化学行为Dy(Ⅲ)和Co(Ⅱ)在Pt电极上分别为一步不可逆还原为Dy(0),Co(0);研究了不同浓度的支持电解质对Dy(Ⅲ)的传递系数的影响;测定并得到0.01mol·dm