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The present research brings new insights on the role of admixed corrosion inhibitors in the processes of cement hydration and rebar corrosion.The admixing of NaCl and the corrosion inhibitors in fresh mortar was found to alter the morphology and microstructure of the hardened mortar at the steel-mortar interfacial region.The admixing of the inhibitors increased the risk of carbonation of cement hydrates at the steel-mortar interfacial region,but partially displaced chloride ions. Chloride and the admixed in... 相似文献
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Bradfield JP Taal HR Timpson NJ Scherag A Lecoeur C Warrington NM Hypponen E Holst C Valcarcel B Thiering E Salem RM Schumacher FR Cousminer DL Sleiman PM Zhao J Berkowitz RI Vimaleswaran KS Jarick I Pennell CE Evans DM St Pourcain B Berry DJ Mook-Kanamori DO Hofman A Rivadeneira F Uitterlinden AG van Duijn CM van der Valk RJ de Jongste JC Postma DS Boomsma DI Gauderman WJ Hassanein MT Lindgren CM Mägi R Boreham CA Neville CE Moreno LA Elliott P Pouta A Hartikainen AL Li M Raitakari O 《Nature genetics》2012,44(5):526-531
Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made in establishing genetic influences on common early-onset obesity. We performed a North American, Australian and European collaborative meta-analysis of 14 studies consisting of 5,530 cases (≥95th percentile of body mass index (BMI)) and 8,318 controls (<50th percentile of BMI) of European ancestry. Taking forward the eight newly discovered signals yielding association with P < 5 × 10(-6) in nine independent data sets (2,818 cases and 4,083 controls), we observed two loci that yielded genome-wide significant combined P values near OLFM4 at 13q14 (rs9568856; P = 1.82 × 10(-9); odds ratio (OR) = 1.22) and within HOXB5 at 17q21 (rs9299; P = 3.54 × 10(-9); OR = 1.14). Both loci continued to show association when two extreme childhood obesity cohorts were included (2,214 cases and 2,674 controls). These two loci also yielded directionally consistent associations in a previous meta-analysis of adult BMI(1). 相似文献
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