面向飞机PHM的大数据分析与人工智能应用

针对新一代电子产品密集型的飞机,其系统结构和失效机理复杂、失效模式多样,传统的方法难以对其进行有效健康管理的现状,因此提出了基于海量数据挖掘的飞机PHM研究。首先从系统结构、服役环境、数据来源与存储方式等角度分析了新一代飞机对海量数据挖掘的应用需求;其次论述了基于海量数据挖掘的关键技术,包括数据的预处理、集成管理、聚类、分类、关联、预测等;最后提出了一种基于私有云的飞机PHM海量数据挖掘平台,详细阐述了该平台的总体框架和软硬件结构,该平台为飞机PHM提供了验证平台,对促进飞机PHM的集成与工程化实现具有重大的军事应用意义。     

Diet and the evolution of human amylase gene copy number variation

Starch consumption is a prominent characteristic of agricultural societies and hunter-gatherers in arid environments. In contrast, rainforest and circum-arctic hunter-gatherers and some pastoralists consume much less starch. This behavioral variation raises the possibility that different selective pressures have acted on amylase, the enzyme responsible for starch hydrolysis. We found that copy number of the salivary amylase gene (AMY1) is correlated positively with salivary amylase protein level and that individuals from populations with high-starch diets have, on average, more AMY1 copies than those with traditionally low-starch diets. Comparisons with other loci in a subset of these populations suggest that the extent of AMY1 copy number differentiation is highly unusual. This example of positive selection on a copy number-variable gene is, to our knowledge, one of the first discovered in the human genome. Higher AMY1 copy numbers and protein levels probably improve the digestion of starchy foods and may buffer against the fitness-reducing effects of intestinal disease.