排序方式: 共有6条查询结果,搜索用时 15 毫秒
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F. M. Goñi J. M. Valpuesta M. C. Barbero E. Rial J. I. G. Gurtubay J. M. Macarulla 《Cellular and molecular life sciences : CMLS》1984,40(2):193-195
Summary The solubilizing effect of Triton X-100 on beef heart submitochondrial particles (ETPH) has been studied under various physiological conditions. Coupled, uncoupled and azide-inhibited ETPH particles have been studied. Quantitative and qualitative differences are found in the proteins solubilized by the detergent from ETPH particles under the various conditions tested.Acknowledgments: This work was supported in part by a grant from a Spanish Comisión Asesora para la Investigación Cientifica y Técnica. M.C. Barbero was recipient of a scholarship from the Basque Government. 相似文献
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F M Go?i J M Valpuesta M C Barbero E Rial J I Gurtubay J M Macarulla 《Experientia》1984,40(2):193-195
The solubilizing effect of Triton X-100 on beef heart submitochondrial particles (ETPH) has been studied under various physiological conditions. Coupled, uncoupled and azide-inhibited ETPH particles have been studied. Quantitative and qualitative differences are found in the proteins solubilized by the detergent from ETPH particles under the various conditions tested. 相似文献
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N. K. Hollenberg Linda R. Barbero K. P. J. Hinrichs 《Cellular and molecular life sciences : CMLS》1971,27(9):1032-1034
Zusammenfassung Die Auffassung, dass die Gewebsangiotensinase-Aktivität entscheidend sei, ob sich eine Gewebs-Tachiphylaxie gegenüber Angiotensin entwickelt oder nicht, konnte durch Versuche an verschiedenartigen Geweben keine Bestätigung finden.
Supported by grants from the John A. Hartford Foundation, Inc., and the U.S. Army R and D Command No. DA-49-193-MD 2497. 相似文献
Supported by grants from the John A. Hartford Foundation, Inc., and the U.S. Army R and D Command No. DA-49-193-MD 2497. 相似文献
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José L. Barbero 《Cellular and molecular life sciences : CMLS》2009,66(13):2025-2035
Cells have evolved to develop molecules and control mechanisms that guarantee correct chromosome segregation and ensure the
proper distribution of genetic material to daughter cells. In this sense, the establishment, maintenance, and removal of sister
chromatid cohesion is one of the most fascinating and dangerous processes in the life of a cell because errors in the control
of these processes frequently lead to cell death or aneuploidy. The main protagonist in this mechanism is a four-protein complex
denominated the cohesin complex. In the last 10 years, we have improved our understanding of the key players in the regulation
of sister chromatid cohesion during cell division in mitosis and meiosis. The last 2 years have seen an increase in evidence
showing that cohesins have important functions in non-dividing cells, revealing new, unexplored roles for these proteins in
the control of gene expression, development, and other essential cell functions in mammals. 相似文献
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Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice 总被引:24,自引:0,他引:24
Ortega S Prieto I Odajima J Martín A Dubus P Sotillo R Barbero JL Malumbres M Barbacid M 《Nature genetics》2003,35(1):25-31
We targeted the locus encoding the cyclin-dependent kinase 2 (CDK2) by homologous recombination in mouse embryonic stem (ES) cells. Embryonic fibroblasts lacking CDK2 proliferate normally and become immortal after continuous passage in culture. Elimination of a conditional Cdk2 allele in immortal cells does not have a significant effect on proliferation. Cdk2-/- mice are viable and survive for up to two years, indicating that CDK2 is also dispensable for proliferation and survival of most cell types. But CDK2 is essential for completion of prophase I during meiotic cell division in male and female germ cells, an unforeseen role for this cell cycle kinase. 相似文献
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