排序方式: 共有3条查询结果,搜索用时 0 毫秒
1
1.
L Deshayes D Lévy G Fournier L Gilly 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1978,286(5):435-438
The use of Staphylococcus aureus for the radio-immunoassay of C-type virus polypeptides provided very specific results and proved to present several advantages over the classical methods of precipitation of immune complexes. 相似文献
2.
Deshayes S Morris MC Divita G Heitz F 《Cellular and molecular life sciences : CMLS》2005,62(16):1839-1849
The main problem of therapeutic efficiency lies in the crossing of cellular membranes. Therefore, significant effort is being made to develop agents which can cross these barriers and deliver therapeutic agents into cellular compartments. In recent years, a large amount of data on the use of peptides as delivery agents has accumulated. Several groups have published the first positive results using peptides for the delivery of therapeutic agents in relevant animal models. These peptides, called cell-penetrating peptides (CPPs), are short peptides (fewer than 30 residues) with a net positive charge and acting in a receptor- and energy-independent manner. Here, we give an extensive review of peptide-mediated delivery systems and discuss their applications, with particular focus on the mechanisms leading to cellular internalization.Received 14 March 2005; received after revision 25 April 2005; accepted 28 April 2005 相似文献
3.
1