A convenient thin layer chromatographic method for the detection of cyclochlorotine and simatoxin, toxins from Penicillium islandicum Sopp

A rapid, convenient TLC method is described for detection of cyclochlorotine, a carcinogen produced by the commonly found storage mold Penicillium islandicum Sopp. This method has also led to the isolation of a new toxic metabolite, simatoxin.     

A convenient thin layer chromatographic method for the detection of cyclochlorotine and simatoxin,toxins fromPenicillium islandicum Sopp

Summary A rapid, convenient TLC method is described for detection of cyclochlorotine, a carcinogen produced by the commonly found storage moldPenicillium islandicum Sopp. This method has also led to the isolation of a new toxic metabolite, simatoxin.Acknowledgment. This work was supported by Food and Drug Administration, Washington, D.C. (Contract No. FDA-223-74-2209).     

Gossypol. Synthesis and in vitro spermicidal activity of isomeric hemigossypol derivatives

Cellular and Molecular Life Sciences - Three isomeric hemigossypol derivatives (3, 4, 5) have been synthesized. Two of these derivatives (3, 4) and one synthetic intermediate (7) have been shown to...